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Titolo:
THE INDUSTRIAL-PRODUCTION OF ENZYMES
Autore:
HEADON DR; WALSH G;
Indirizzi:
NATL UNIV IRELAND UNIV COLL GALWAY,DEPT BIOCHEM,CELL & MOLEC BIOL GRPGALWAY IRELAND
Titolo Testata:
Biotechnology advances
fascicolo: 4, volume: 12, anno: 1994,
pagine: 635 - 646
SICI:
0734-9750(1994)12:4<635:TIOE>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
PLASMINOGEN-ACTIVATOR; EXPRESSION; CHYMOSIN; PURIFICATION; SECRETION; STARCH; FUNGI;
Keywords:
ENZYMES; RECOMBINANT DNA; AMYLASE; INDUSTRIAL ENZYME PRODUCTION;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
35
Recensione:
Indirizzi per estratti:
Citazione:
D.R. Headon e G. Walsh, "THE INDUSTRIAL-PRODUCTION OF ENZYMES", Biotechnology advances, 12(4), 1994, pp. 635-646

Abstract

The production of enzymes is a pursuit central to the modern biotechnology industry. Markets for traditional industrial enzymes continue togrow while the continued emphasis on biotechnological endeavours has generated demand for an ever increasing number of additional biocatalysts. The advent of genetic engineering has now facilitated the large-scale production of enzymes and other proteins which are produced naturally only in minute quantities. This development is particularly significant with regard to the production of enzymes and other proteins of therapeutic significance, which are now available in clinically usefulquantities. The level of downstream processing to which any enzyme issubjected is dependent upon its intended application. Industrial enzymes produced in bulk generally require little downstream processing, and hence are relatively crude preparations. Enzymes destined for therapeutic applications are subject to a far higher degree of downstream processing, often incorporating 3-4 chromatographic steps. While enzymology is one of the longest established branches of the biochemical sciences, it continues to be an area of ongoing, active research. The continual discovery of new enzymes and a greater understanding of previously discovered enzymes and their functional significance suggests manynovel applications for these catalytic activities. The intestinal production and utilization of enzymes will continue to be of central importance in the biotechnology industry.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/09/20 alle ore 11:19:24