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Titolo:
GIANT-CELL ARTERITIS - VALIDITY AND RELIABILITY OF VARIOUS DIAGNOSTIC-CRITERIA
Autore:
HAYREH SS; PODHAJSKY PA; RAMAN R; ZIMMERMAN B;
Indirizzi:
UNIV IOWA HOSP & CLIN,DEPT OPHTHALMOL,200 HAWKINS DR IOWA CITY IA 52242 UNIV IOWA,DEPT OPHTHALMOL,COLL MED IOWA CITY IA 52242 UNIV IOWA,DEPT PREVENT MED & ENVIRONM HLTH,COLL MED IOWA CITY IA 52242
Titolo Testata:
American journal of ophthalmology
fascicolo: 3, volume: 123, anno: 1997,
pagine: 285 - 296
SICI:
0002-9394(1997)123:3<285:GA-VAR>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
ERYTHROCYTE SEDIMENTATION-RATE; ISCHEMIC OPTIC NEUROPATHY; TEMPORAL ARTERITIS; POLYMYALGIA RHEUMATICA; BIOPSY; ANTIBODIES; FEATURES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
42
Recensione:
Indirizzi per estratti:
Citazione:
S.S. Hayreh et al., "GIANT-CELL ARTERITIS - VALIDITY AND RELIABILITY OF VARIOUS DIAGNOSTIC-CRITERIA", American journal of ophthalmology, 123(3), 1997, pp. 285-296

Abstract

PURPOSE: To ascertain the validity, reliability, sensitivity, and specificity of: various signs and symptoms of and diagnostic tests for early diagnosis of giant cell arteritis. METHODS: From 1973 to 1994, we studied 363 patients who had temporal artery biopsy for suspected giant cell arteritis. All patients underwent detailed clinical evaluation and had erythrocyte sedimentation rates determined; since 1985, 223 patients had their C-reactive protein values estimated. Erythrocyte sedimentation rate and C-reactive protein levels were also estimated in 749 and 138 control subjects, respectively. Signs and symptoms of giant cell arteritis, erythrocyte sedimentation rate, and C-reactive proteinlevels among patients with positive and negative biopsies were compared. RESULTS: Of the 363 patients, temporal artery biopsy was positive in 106 and negative in 257. The odds of a positive biopsy were 9.0 times greater with jaw claudication (P < .0001), 3.4 times greater with neck pain (P = .0085), 2.0 times greater with an erythrocyte sedimentation rate of 47 to 107 mm/hour (P = .0454), 3.2 times greater with C-reactive protein above 2.45 mg/dl (P = .0208), and 2.0 times greater forage 75 years or more (P = .0105). CONCLUSIONS: Clinical criteria moststrongly suggestive of giant cell arteritis include jaw claudication,C-reactive protein above 2.45 mg/dl, neck pain, and an erythrocyte sedimentation rate of 47 mm/hour or more, in that order. C-reactive protein was more sensitive (100%) than erythrocyte sedimentation rate (92%) for detection of giant cell arteritis; erythrocyte sedimentation rate combined with C-reactive protein gave the best specificity (97%).

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/10/20 alle ore 00:32:44