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Titolo:
RISK-FACTORS FOR EXERCISE-INDUCED SILENT-MYOCARDIAL-ISCHEMIA IN HEALTHY-VOLUNTEERS
Autore:
KATZEL LI; SORKIN JD; COLMAN E; GOLDBERG AP; BUSBYWHITEHEAD MJ; LAKATTA LE; BECKER LC; LAKATTA EG; FLEG JL;
Indirizzi:
VET AFFAIRS MED CTR,CTR GERIATR RES EDUC & CLIN,GERIATR SERV 18,METABSECT,CLIN PHYSIOL LAB BALTIMORE MD 21201 UNIV MARYLAND,SCH MED,DEPT MED,DIV GERONTOL BALTIMORE MD 21201 NIA,GERONTOL RES CTR,CARDIOVASC SCI LAB BALTIMORE MD 21224 JOHNS HOPKINS UNIV,SCH MED,DEPT MED,DIV GERIAT MED & GERONTOL BALTIMORE MD 21205 JOHNS HOPKINS UNIV,SCH MED,DEPT MED,DIV CARDIOL BALTIMORE MD 21205 FRANCIS SCOTT KEY MED CTR BALTIMORE MD 21224
Titolo Testata:
The American journal of cardiology
fascicolo: 9, volume: 74, anno: 1994,
pagine: 869 - 874
SICI:
0002-9149(1994)74:9<869:RFESIH>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
DENSITY-LIPOPROTEIN CHOLESTEROL; CORONARY-ARTERY DISEASE; OLDER MEN; ASYMPTOMATIC MEN; SCINTIGRAPHY; MORTALITY; OBESITY; PROGNOSIS; PATIENT; FOLLOW;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
30
Recensione:
Indirizzi per estratti:
Citazione:
L.I. Katzel et al., "RISK-FACTORS FOR EXERCISE-INDUCED SILENT-MYOCARDIAL-ISCHEMIA IN HEALTHY-VOLUNTEERS", The American journal of cardiology, 74(9), 1994, pp. 869-874

Abstract

This study determined the risk factors for exercise-induced silent ischemia (SI) in 281 apparently healthy volunteers aged 40 to 87 years and compared their risk factor profiles with those of 132 patients withovert coronary artery disease (CAD). SI (concordant exercise-induced asymptomatic ST-segment depression on electrocardiography and perfusion defects on tomographic thallium-201 scintigraphy) was detected in 37of 225 men (16%), versus 2 of 56 women (4%, p <0.05). The prevalence of SI increased with age from 6% in men aged <55 years to 18% in men aged 55 to 70 years, and to 25% in men aged >70 years (p <0.001). Compared with the 118 men with concordant normal exercise electrocardiogramand thallium scan (normals), men with SI were older (p <0.001), and had a higher waist-to-hip ratio (p <0.005), higher plasma triglyceride levels (p <0.001), and lower high-density lipoprotein (HDL) cholesterol levels (p <0.001). In stepwise logistic regression analysis, age, waist-to-hip ratio, and HDL levels were independent predictors of SI in men. Compared with 108 men with overt CAD, men with SI were younger (67 +/- 2 vs 73 +/- 1 years, p <0.001) but had similar plasma lipids andwaist-to-hip ratio. Thus, older age, male gender, abdominal obesity, and reduced HDL levels-all well-established risk factors for overt CAD-were risk factors for exercise-induced SI in these asymptomatic volunteers.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 01:50:40