Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
DIABETES AND DIABETES RISK-FACTORS IN 2ND-GENERATION AND 3RD-GENERATION JAPANESE-AMERICANS IN SEATTLE, WASHINGTON
Autore:
FUJIMOTO WY; BERGSTROM RW; BOYKO EJ; KINYOUN JL; LEONETTI DL; NEWELLMORRIS LL; ROBINSON LR; SHUMAN WP; STOLOV WC; TSUNEHARA CH; WAHL PW;
Indirizzi:
UNIV WASHINGTON,DEPT MED,DIV METAB ENDOCRINOL & NUTR,RG-26 SEATTLE WA98195 UNIV WASHINGTON,DEPT OPHTHALMOL SEATTLE WA 98195 UNIV WASHINGTON,DEPT ANTHROPOL SEATTLE WA 98195 UNIV WASHINGTON,DEPT REHABIL MED SEATTLE WA 98195 UNIV WASHINGTON,DEPT RADIOL SEATTLE WA 98195 UNIV WASHINGTON,DEPT BIOSTAT SEATTLE WA 98195
Titolo Testata:
Diabetes research and clinical practice
, volume: 24, anno: 1994, supplemento:, S
pagine: 190000043 - 190000052
SICI:
0168-8227(1994)24:<190000043:DADRI2>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
IMPAIRED GLUCOSE-TOLERANCE; BODY-FAT DISTRIBUTION; CARDIOVASCULAR RISK; PHYSICAL-ACTIVITY; C-PEPTIDE; MEN; INSULIN; MELLITUS; PREVALENCE; INTOLERANCE;
Keywords:
BODY FAT DISTRIBUTION; COMPLICATIONS; CORONARY HEART DISEASE; DIABETES; EPIDEMIOLOGY; HYPERTENSION; IMPAIRED GLUCOSE TOLERANCE; INSULIN RESISTANCE SYNDROME; LIFE-STYLE; JAPANESE-AMERICAN; GENDER;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
37
Recensione:
Indirizzi per estratti:
Citazione:
W.Y. Fujimoto et al., "DIABETES AND DIABETES RISK-FACTORS IN 2ND-GENERATION AND 3RD-GENERATION JAPANESE-AMERICANS IN SEATTLE, WASHINGTON", Diabetes research and clinical practice, 24, 1994, pp. 190000043-190000052

Abstract

In seattle, Washington, the prevalence of diabetes was 20% in second-generation (Nisei) Japanese-American men and 16% in Nisei women 45-74 years old, while the prevalence of impaired glucose tolerance (IGT) was 36% in Nisei men and 40% in Nisei women. Hyperglycemia was less and duration of diabetes shorter in women. Related to diabetes and IGT in Nisei were higher fasting plasma insulin levels and central (visceral)adiposity. Prevalence of diabetes was low among the younger (34-53 year old) third-generation (sansei) men and women. Among self-reported non-diabetic Sansei, however, prevalence of IGT was 19% in men and 29% in women, and IGT was associated with both increased fasting plasma insulin levels and more visceral fat, suggesting that many Sansei are atrisk of future diabetes. An important lifestyle factor in the development of NIDD in Japanese Americans appeared to be dietary saturated (animal) fat. Another factor may be physical inactivity. In Japanese-American women, menopause also appeared to be an important risk factor. These risk factors may be related to fostering the accumulation of visceral fat and the development of insulin resistance. Five-year follow-up examinations performed in non-diabetic Nisei men and women have yielded additional information concerning the prognosis of IGT. Of those women who were IGT at baseline, 34% were diabetic at follow-up while 17% returned to normal. In men who had been IGT at baseline, 18% were diabetic at follow-up while 36% returned to normal. Over the 5-yr follow-up interval, proportionally more women progressed from normal to IGT (54%) then went from IGT to normal (17%). For men, roughly equal proportions went from normal to IGT (37%) as from IGT to normal (36%). It would therefore appear that greater proportions of Nisei women are progressing to IGT and to NIDD than are Nisei men. This observation may berelated to the increased risk of developing central obesity and insulin resistance following menopause. Prevalence of cardiovascular disease (hypertension, peripheral vascular disease, and/or coronary heart disease) was increased in Japanese Americans with IGT and NIDD. Neuropathy and retinopathy were associated only with NIDD.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 10:44:29