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Titolo:
BIOCHEMICAL INDEXES AND NEUROMUSCULAR FUNCTION-TESTS IN RURAL GAMBIANSCHOOLCHILDREN GIVEN A RIBOFLAVIN, OR MULTIVITAMIN PLUS IRON, SUPPLEMENT
Autore:
BATES CJ; EVANS PH; ALLISON G; SONKO BJ; HOARE S; GOODRICH S; ASPRAY T;
Indirizzi:
MRC,DUNN NUTR UNIT,MILTON RD CAMBRIDGE CB4 1XJ ENGLAND MRC,APPL PSYCHOL UNIT CAMBRIDGE CB2 2EF ENGLAND
Titolo Testata:
British Journal of Nutrition
fascicolo: 4, volume: 72, anno: 1994,
pagine: 601 - 610
SICI:
0007-1145(1994)72:4<601:BIANFI>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
VITAMIN STATUS; SCHOOL BOYS; CHILDREN; DEFICIENCY; ANALYZER; IMPACT; ANEMIA; ASSAY;
Keywords:
VITAMIN SUPPLEMENT; THIRD-WORLD CHILDREN; NEUROMUSCULAR TESTS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
30
Recensione:
Indirizzi per estratti:
Citazione:
C.J. Bates et al., "BIOCHEMICAL INDEXES AND NEUROMUSCULAR FUNCTION-TESTS IN RURAL GAMBIANSCHOOLCHILDREN GIVEN A RIBOFLAVIN, OR MULTIVITAMIN PLUS IRON, SUPPLEMENT", British Journal of Nutrition, 72(4), 1994, pp. 601-610

Abstract

Ninety preselected children, aged between 8 and 14 years, living in two rural West African (Gambian) villages, mere randomly divided into three groups, matched for age and sex. One group received a placebo (lactose) tablet, one received riboflavin (5 mg) on 5 d every week,,whichwas sufficient to correct an endemic riboflavin deficiency, and one received a multivitamin supplement (Protovit; Hoffmann La Roche), on 5 d every week, together with FeSO4 (200 mg) once weekly, and the supplements were given for 1 year. Neuromuscular tests, including arm tremorand manipulative skills, were performed on three occasions: once justbefore the introduction of the supplements; again 6 weeks after commencing the supplements; and again 1 year later. Venous blood samples were collected at the same time as the first two sets of neuromuscular tests. These samples were used for haematology and nutrient status indices: plasma ferritin, ascorbic acid, cyanocobalamin and pyridoxal phosphate, and erythrocyte tests for folate status, for riboflavin status (erythrocyte glutathione reductase activation coefficient) and thiamine status (erythrocyte transketolase activation coefficient). The riboflavin in both supplements achieved a clear-cut response in biochemicalstatus, which was dose-dependent. The pyridoxine, ascorbic acid and Fe components of the multivitamin also affected the associated biochemical indices. Although overall the arm tremor and related neuromuscularfunction tests did not respond significantly to the supplements, significant improvement was seen in the boys for the arm-tremor test in both the supplemented groups.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/10/20 alle ore 05:20:59