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Titolo:
TIAPRIDE IN THE PREVENTION OF RELAPSE IN RECENTLY DETOXIFIED ALCOHOLICS
Autore:
SHAW GK; WALLER S; MAJUMDAR SK; ALBERTS JL; LATHAM CJ; DUNN G;
Indirizzi:
BEXLEY HOSP,OLD BEXLEY LANE BEXLEY DA5 2BW KENT ENGLAND UNIV LONDON GOLDSMITHS COLL LONDON SE14 6NW ENGLAND INST PSYCHIAT,DEPT BIOSTAT LONDON ENGLAND
Titolo Testata:
British Journal of Psychiatry
, volume: 165, anno: 1994,
pagine: 515 - 523
SICI:
0007-1250(1994)165:<515:TITPOR>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
VALIDITY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social Sciences Citation Index
Science Citation Index Expanded
Citazioni:
15
Recensione:
Indirizzi per estratti:
Citazione:
G.K. Shaw et al., "TIAPRIDE IN THE PREVENTION OF RELAPSE IN RECENTLY DETOXIFIED ALCOHOLICS", British Journal of Psychiatry, 165, 1994, pp. 515-523

Abstract

Background. The aim was to investigate the effect of tiapride (100 mgthree times a day for at least one month) on outcome following detoxification. Method. The setting was a tertiary referral centre. The study design was randomised, double-blind, and placebo-controlled. One hundred routinely admitted alcohol-dependent patients were entered, and 54 completed the trial. Outcome was assessed by considering drinking status at three months and six months follow-up, and by comparing psychological status at intake and follow-up using the Crown-Crisp Experiential Index, the Litman Self-esteem scale and a Satisfaction with Life Situations scale. We also compared performance over the six months before admission with the three and six months of follow-up on measures ofhealth, social and drinking variables. Results. Tiapride proved better (usually at statistically highly significant levels) than placebo atpromoting: abstinence, self-esteem, and satisfaction with life situations; and at reducing: alcohol consumption, use of health service resources, and levels of neuroticism. Conclusions. Tiapride merits seriousconsideration in the longer-term treatment of alcoholic patients.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/09/20 alle ore 18:18:42