Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
BIDIRECTIONAL EFFECTS OF INTRATHECAL NMDA AND SUBSTANCE-P ON RAT DORSAL HORN NEURONAL RESPONSES
Autore:
CHAPMAN V; DICKENSON AH; TJOLSEN A;
Indirizzi:
INSERM,U161,2 RUE ALESIA F-75014 PARIS FRANCE UNIV COLL LONDON,DEPT PHARMACOL LONDON WC1E 6BT ENGLAND UNIV BERGEN,DEPT PHYSIOL N-5009 BERGEN NORWAY
Titolo Testata:
Neuroscience letters
fascicolo: 1, volume: 178, anno: 1994,
pagine: 90 - 94
SICI:
0304-3940(1994)178:1<90:BEOINA>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
EXCITATORY AMINO-ACIDS; C-FIBER STIMULATION; NOCICEPTIVE NEURONS; SPINAL-CORD; RECEPTORS; CAT; POTENTIATION; TRANSMISSION; INVOLVEMENT; TACHYKININS;
Keywords:
RAT; DORSAL HORN; NOCICEPTION; N-METHYL-D-ASPARTATE; SUBSTANCE P;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
21
Recensione:
Indirizzi per estratti:
Citazione:
V. Chapman et al., "BIDIRECTIONAL EFFECTS OF INTRATHECAL NMDA AND SUBSTANCE-P ON RAT DORSAL HORN NEURONAL RESPONSES", Neuroscience letters, 178(1), 1994, pp. 90-94

Abstract

Intrathecal NMDA (5 ng) facilitated wind-up but not C-fibre evoked responses, whereas 50 ng facilitated C-fibre and A delta-fibre evoked responses but not wind-up of convergent dorsal born neurones in the halothane anaesthetized rat. Higher doses of NMDA and SP (10-500 ng) were without effect. Co-administered SP (10 ng) with NMDA (5 ng) facilitated A delta-fibre evoked responses and wind-up. Excitatory amino acid and peptide interactions are discussed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 15/07/20 alle ore 08:26:59