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Titolo:
DIFFERENT MODIFICATIONS OF THE DOPAMINE METABOLISM IN THE CORE AND SHELL PARTS OF THE NUCLEUS-ACCUMBENS FOLLOWING CCK-A RECEPTOR STIMULATION IN THE SHELL REGION
Autore:
LADURELLE N; DURIEUX C; ROQUES BP; DAUGE V;
Indirizzi:
UNIV PARIS 05,FAC SCI PHARMACEUT & BIOL,DEPT PHARMACOCHIM MOLEC & STRUCT,CNRS URA D 1500 F-75270 PARIS 06 FRANCE UNIV PARIS 05,FAC SCI PHARMACEUT & BIOL,DEPT PHARMACOCHIM MOLEC & STRUCT,CNRS URA D 1500 F-75270 PARIS 06 FRANCE
Titolo Testata:
Neuroscience letters
fascicolo: 1, volume: 178, anno: 1994,
pagine: 5 - 10
SICI:
0304-3940(1994)178:1<5:DMOTDM>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
CHOLECYSTOKININ-LIKE; PHARMACOLOGICAL CHARACTERIZATION; INVIVO RELEASE; RAT-BRAIN; NEURONS; )H-3>DOPAMINE; OCTAPEPTIDE; MODULATION; INJECTION; PEPTIDES;
Keywords:
NUCLEUS ACCUMBENS SHELL AND CORE; CHOLECYSTOKININ; CCK-A RECEPTOR; DOPAMINE METABOLISM; EX VIVO TISSUE PUNCHES; RAT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
28
Recensione:
Indirizzi per estratti:
Citazione:
N. Ladurelle et al., "DIFFERENT MODIFICATIONS OF THE DOPAMINE METABOLISM IN THE CORE AND SHELL PARTS OF THE NUCLEUS-ACCUMBENS FOLLOWING CCK-A RECEPTOR STIMULATION IN THE SHELL REGION", Neuroscience letters, 178(1), 1994, pp. 5-10

Abstract

After the injection of CCK8 into the posterior N. Acc. of rats, DA, DOPAC and HVA contents were determined from punches of the anterior andposterior N. Acc. and VTA. CCK8 (20 pmol/side) modified these levels only in the posterior N. Acc. and these responses were inhibited by the CCK-A antagonist devazepide. Five min after treatment, DA, DOPAC andHVA were increased in the N. Acc.(shell) and 10 min later they were decreased in the N. Acc.(core). These data suggest that in these regions CCK8 could both abolish the influence of DA from the core on the transmission of motor information and favor that of DA from the shell on emotional-like responses.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 16/07/20 alle ore 06:36:56