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Titolo:
CONFORMITY WITH GUIDELINES FOR ANTIMICROBIAL PROPHYLAXIS AGAINST BACTERIAL-ENDOCARDITIS
Autore:
SAGERT G; AUSTIN TW; BOMBASSARO AM; PARBTANI A;
Indirizzi:
VICTORIA HOSP,CLIN PHARM SERV,800 COMMISSIONERS RD E LONDON N6A 4G5 ON CANADA VICTORIA HOSP,CLIN PHARM SERV LONDON N6A 4G5 ON CANADA MT SINAI HOSP TORONTO ON CANADA UNIV WESTERN ONTARIO LONDON ON CANADA
Titolo Testata:
American journal of hospital pharmacy
fascicolo: 19, volume: 51, anno: 1994,
pagine: 2403 - 2408
SICI:
0002-9289(1994)51:19<2403:CWGFAP>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
AMERICAN-HEART-ASSOCIATION; INFECTIVE-ENDOCARDITIS; ANTIBIOTIC-PROPHYLAXIS; PREVENTION; RECOMMENDATIONS; EFFICACY;
Keywords:
AMERICAN HEART ASSOCIATION; ANTIINFECTIVE AGENTS; COMPLIANCE; DOSAGE SCHEDULES; ENDOCARDITIS; GUIDELINES; PEDIATRICS; RATIONAL THERAPY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
16
Recensione:
Indirizzi per estratti:
Citazione:
G. Sagert et al., "CONFORMITY WITH GUIDELINES FOR ANTIMICROBIAL PROPHYLAXIS AGAINST BACTERIAL-ENDOCARDITIS", American journal of hospital pharmacy, 51(19), 1994, pp. 2403-2408

Abstract

The extent to which prescribed antimicrobial prophylaxis against bacterial endocarditis conformed with American Heart Association (AHA) guidelines was determined and the frequency of nonconformity with specific elements of the guidelines was evaluated. Patients with conditions defined by AHA as placing them at risk for developing endocarditis wereidentified through medical records for a four-year period at an 850-bed hospital. Data about the procedures they underwent and prophylaxis prescribed were compared with the AHA guidelines. Conformity with guidelines was evaluated according to whether prophylaxis was recommended,optional, or unnecessary; nonconformity with specific elements of theguidelines (indication, choice of antimicrobial, dose, dosage interval, timing, and duration) was also evaluated. The following variables were evaluated for possible association with nonconformity to the guidelines: patient's age and sex, penicillin allergy, use of a consultant,and whether the procedure was the first performed in the patient after identification of the cardiac condition. Of the 131 cases analyzed, 29 (22%) involved prophylaxis that conformed with the AHA guidelines. Conformity with the guidelines was significantly lower when prophylaxis was recommended or optional than when it was unnecessary. Nonconformity was most common with the following elements: indication, choice ofantimicrobial, and dose. Recommended prophylaxis was given more oftenin children than in adults and more often before first procedures than before subsequent procedures. More of the regimens prescribed for children exceeded the recommended duration than those prescribed for adults. Unnecessary prophylaxis was given more often when a consultant was involved than when no consultant was involved. In hospitalized patients conformity with AHA guidelines for antimicrobial prophylaxis against endocarditis was low.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/08/20 alle ore 00:52:25