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Titolo:
CIRCADIAN VARIATIONS OF ATRIAL-NATRIURETIC-PEPTIDE IN NORMAL PEOPLE AND ITS RELATIONSHIP TO ARTERIAL BLOOD-PRESSURE, PLASMA-RENIN ACTIVITY AND ALDOSTERONE LEVEL
Autore:
CHIANG FT; TSENG CD; HSU KL; LO HM; TSENG YZ; HSIEH PS; WU TL;
Indirizzi:
NATL TAIWAN UNIV,COLL MED,DEPT LAB MED,1 CHAN TEH ST TAIPEI 10016 TAIWAN NATL TAIWAN UNIV,COLL MED,DEPT INTERNAL MED TAIPEI 10016 TAIWAN
Titolo Testata:
International journal of cardiology
fascicolo: 3, volume: 46, anno: 1994,
pagine: 229 - 233
SICI:
0167-5273(1994)46:3<229:CVOAIN>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
EXTRACT; RELEASE; HORMONE;
Keywords:
CIRCADIAN VARIATION; ATRIAL NATRIURETIC PEPTIDE; BLOOD PRESSURE; ALDOSTERONE; RENIN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
13
Recensione:
Indirizzi per estratti:
Citazione:
F.T. Chiang et al., "CIRCADIAN VARIATIONS OF ATRIAL-NATRIURETIC-PEPTIDE IN NORMAL PEOPLE AND ITS RELATIONSHIP TO ARTERIAL BLOOD-PRESSURE, PLASMA-RENIN ACTIVITY AND ALDOSTERONE LEVEL", International journal of cardiology, 46(3), 1994, pp. 229-233

Abstract

To investigate the circadian variations of plasma atrial natriuretic peptide (ANP) and its relationship to arterial blood pressure, plasma renin activity and aldosterone level, we determined 24-h blood pressure in 14 healthy volunteers. Plasma ANP concentration, renin activity and aldosterone levels were measured every 3 h by radioimmunoassay. We found no significant circadian variation of plasma ANP level (pg/ml) (daytime level, 62 +/- 24 vs. night-time level, 57 +/- 19, P = 0.146) and plasma renin level (ng/ml/h) (1.32 +/- 0.78 vs. 1.15 +/- 0.57, P = 0.148), but there was diurnal change of blood pressure (mmHg) (systolic, 122 +/- 7 vs. 116 +/- 11, P < 0.001; diastolic, 80 +/- 11 vs. 72 +/- 11, P = 0.025) and plasma aldosterone level (pg/ml) (86 +/- 42 vs. 62 +/- 37, P < 0.001). The blood pressure and aldosterone levels reached maxima (11:00 h and 08:00 h, respectively) before that of ANP (17:00h) and then decreased together until the nadir at 02:00 h. This mightindicate that elevation of arterial blood pressure and plasma aldosterone level stimulate release of ANP under normal physiological conditions.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 15/07/20 alle ore 21:25:58