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Titolo:
THE STABILITY OF DUPLEX DNA CONTAINING 3,N-4-ETHENO-2'-DEOXYCYTIDINE (EPSILON-DC) - A UV MELTING AND HIGH-RESOLUTION H-1-NMR STUDY
Autore:
GIBSON NJ; PARKINSON JA; BARLOW T; WATSON WP; BROWN T;
Indirizzi:
UNIV EDINBURGH,DEPT CHEM,KINGS BLDG,W MAINS RD EDINBURGH EH9 3JJ MIDLOTHIAN SCOTLAND UNIV EDINBURGH,DEPT CHEM EDINBURGH EH9 3JJ MIDLOTHIAN SCOTLAND SHELL RES LTD,SITTINGBOURNE RES CTR SITTINGBOURNE ME9 8AG KENT ENGLAND
Titolo Testata:
Journal of the Chemical Society, Chemical Communications
fascicolo: 19, , anno: 1994,
pagine: 2241 - 2242
SICI:
0022-4936(1994):19<2241:TSODDC>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
SITE-SPECIFIC ETHENOCYTOSINE; VINYL-CHLORIDE; MUTAGENESIS; MECHANISMS; ADDUCTS; METABOLITES; BEARING; LESION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
12
Recensione:
Indirizzi per estratti:
Citazione:
N.J. Gibson et al., "THE STABILITY OF DUPLEX DNA CONTAINING 3,N-4-ETHENO-2'-DEOXYCYTIDINE (EPSILON-DC) - A UV MELTING AND HIGH-RESOLUTION H-1-NMR STUDY", Journal of the Chemical Society, Chemical Communications, (19), 1994, pp. 2241-2242

Abstract

The mutagenic lesion 3,N-4-etheno-2'-deoxycytidine (epsilon dC) greatly destabilises DNA when paired with each of the natural bases although the solution structure of a duplex containing a epsilon C : A pair shows that the lesion does not greatly disrupt base pairing in the duplex.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/07/20 alle ore 12:23:16