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Titolo:
ASSESSMENT OF LEFT-VENTRICULAR STIFFNESS AND COMPLIANCE
Autore:
MAINTAS D; EGROIZARD P; DAMIEN J; GERONICOLA X; VLONTZOU L; BONTEMPS L; PERINETTI M; BRION R; STAMATELOPOULOS S; KOSTAMIS P; ITTI R; MOULOPOULOS S;
Indirizzi:
UNIV CLAUDE BERNARD & CARDIOL HOSP,BIOPHYS LAB,59 BD PINEL F-69003 LYON FRANCE ATHENS MED CTR,INST ISOTOP STUDIES MAROUSSI GREECE HOP INSTRUC ARMEES LYON FRANCE ALEXANDRA HOSP,DEPT CLIN THERAPEUT ATHENS GREECE
Titolo Testata:
Nuclear medicine communications
fascicolo: 10, volume: 15, anno: 1994,
pagine: 836 - 844
SICI:
0143-3636(1994)15:10<836:AOLSAC>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
TRANSMITRAL FLOW VELOCITY; DIASTOLIC FUNCTION; DOPPLER ECHOCARDIOGRAPHY; PRESSURE; PERFORMANCE; RELAXATION; PROFILE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
17
Recensione:
Indirizzi per estratti:
Citazione:
D. Maintas et al., "ASSESSMENT OF LEFT-VENTRICULAR STIFFNESS AND COMPLIANCE", Nuclear medicine communications, 15(10), 1994, pp. 836-844

Abstract

Invasive and non-invasive methods exist to assess left ventricular compliance (LVC). This work has two parts, one experimental and one clinical. We estimated left chamber stiffness in dogs by using volume datafrom radionuclide ventriculography (RNV) and left ventricular pressure data, synchronized with a gating system to the intraventricular dp/dt max to obtain volume and pressure data from a mean cardiac cycle. Infive dogs after acute experimental ischaemia, the modulus chamber stiffness Kp rose from 30.2+/-4.4 to 55.4+/-5.9 (P<0.01). In 10 dogs withexperimental infarction after intra-aortic balloon pumping, Kp decreased from 33.7+/-5.0 to 15.5+/-3.9 (P<0.01) and in five dogs with experimental infarction, after intravenous infusion of sodium nitroprusside, Kp decreased from 41.4+/-5.5 to 22.2+/-2.8 (P<0.01). In eight normalvolunteers and in 20 postmyocardial infarction patients, we estimateda parameter reflecting the LVC by using volume data with blood flow velocity at the mitral valve annulus. Assuming that the mitral flow-velocity variation reflects LV pressure changes, the formula LVC = (dv/dt)/(dp-dt) becomes (dv/dt)/(df/dt) = dv/df. Values obtained in normals were 0.841+/-0.295 m-1s and after myocardial infarction 0.331+/-0.10 m-1s. Both methods allow clear separation in groups of animals or patients according to the expected changes in LVC or stiffness.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/12/20 alle ore 07:29:10