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Titolo:
TOTAL SYNTHESIS OF NOVEL CONDURITOL RELATED-COMPOUNDS CAPABLE OF MODULATING INSULIN RELEASE
Autore:
BILLINGTON DC; PERRONSIERRA F; PICARD I; BEAUBRAS S; DUHAULT J; ESPINAL J; CHALLAL S;
Indirizzi:
INST RECH SERVIER,DEPT MED CHEM,11 RUE MOULINEAUX F-92150 SURESNES FRANCE INST RECH SERVIER,DEPT METAB DIS F-92150 SURESNES FRANCE
Titolo Testata:
Bioorganic & medicinal chemistry letters
fascicolo: 19, volume: 4, anno: 1994,
pagine: 2307 - 2312
SICI:
0960-894X(1994)4:19<2307:TSONCR>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
MICROBIAL OXIDATION; GYMNEMA-SYLVESTRE; BENZENE; (-)-CONDURITOL-C;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
22
Recensione:
Indirizzi per estratti:
Citazione:
D.C. Billington et al., "TOTAL SYNTHESIS OF NOVEL CONDURITOL RELATED-COMPOUNDS CAPABLE OF MODULATING INSULIN RELEASE", Bioorganic & medicinal chemistry letters, 4(19), 1994, pp. 2307-2312

Abstract

The syntheses of the six isomeric conduritols A - F, and of a series of bicyclic and tricyclic polyols related to the conduritols are described. Conduritols A and B, and representative analogues are able to modulate the release of insulin from isolated pancreatic islets in the presence of varying concentrations of glucose, in both a stimulatory and an inhibitory sense.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/09/20 alle ore 11:29:09