Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
USE OF MODEL MICROORGANISM TO STUDY CYTOSTATICS-MEMBRANE INTERACTIONS
Autore:
LUXO PC; JURADO AS; ALMEIDA LM; MADEIRA VMC;
Indirizzi:
UNIV COIMBRA,MICROBIOL LAB P-3049 COIMBRA PORTUGAL UNIV COIMBRA,FAC FARM,BIOQUIM LAB P-3049 COIMBRA PORTUGAL UNIV COIMBRA,CTR BIOL CELULAR P-3049 COIMBRA PORTUGAL
Titolo Testata:
Toxicology in vitro
fascicolo: 4, volume: 8, anno: 1994,
pagine: 589 - 591
SICI:
0887-2333(1994)8:4<589:UOMMTS>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
FLUIDITY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
9
Recensione:
Indirizzi per estratti:
Citazione:
P.C. Luxo et al., "USE OF MODEL MICROORGANISM TO STUDY CYTOSTATICS-MEMBRANE INTERACTIONS", Toxicology in vitro, 8(4), 1994, pp. 589-591

Abstract

A strain of Bacillus stearothermophilus was used as a model system toelucidate the interaction of tamoxifen with the cell membrane. This drug inhibits bacterial growth in a concentration-dependent manner. Theinhibition increases at suboptimal and supraoptimal temperatures and is attenuated by the addition of Ca2+ to the growth medium. Opposed physical alterations on bacterial membranes were observed when tamoxifenwas added to the growth medium (increase in structural order) or directly in liposome preparations (decrease in structural order).

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/07/20 alle ore 12:54:39