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Titolo:
BRAIN IMAGING IN PSYCHIATRY - FUTURE POSS IBILITIES
Autore:
SEDVALL G;
Indirizzi:
KAROLINSKA INST,DIV PSYCHIAT & PSYCHOL,POB 60500 S-10401 STOCKHOLM 60SWEDEN
Titolo Testata:
Fortschritte der Neurologie, Psychiatrie
, volume: 62, anno: 1994,
pagine: 39 - 43
SICI:
0720-4299(1994)62:<39:BIIP-F>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
GER
Soggetto:
D2-DOPAMINE RECEPTOR OCCUPANCY; LIVING HUMAN-BRAIN; PET; SCHIZOPHRENIA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
8
Recensione:
Indirizzi per estratti:
Citazione:
G. Sedvall, "BRAIN IMAGING IN PSYCHIATRY - FUTURE POSS IBILITIES", Fortschritte der Neurologie, Psychiatrie, 62, 1994, pp. 39-43

Abstract

The brain imaging technics computerized tomography (CT), positron emission tomography (PET) and nuclear magnetic resonance imaging (MRI) represent significant tools for a further categorization of psychiatric patients with regard to brain structure and function. Of these technics PET has the unique sensitivity to examine several aspects of brain function as blood flow, metabolic rates and neurotransmitter mechanisms. Since several decades monaminergic transmitter mechanisms have been implicated in the pathophysiology of schizophrenia and affective disorders as well as in the action of several psychoactive drugs. With regard to schizophrenia and the mechanism of action of antipsychotic drugsDopamine receptors are in the focus of interest. In order to analyze distribution and binding characteristics of dopamine receptor subtypesin the living brain in relation to neuropsychiatric disorders and antipsychotic drug treatment we developed C-11-Labelled selective ligandsbinding to dopamine receptor subtypes and used them in in vivo PET experiments on human subjects.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 09:15:05