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Titolo:
CONTINUOUS MEASUREMENT OF HEMODYNAMIC-ALTERATIONS DURING PHARMACOLOGICAL CARDIOVASCULAR STRESS USING AUTOMATED IMPEDANCE CARDIOGRAPHY
Autore:
SCHERHAG AW; PFLEGER S; DEMEY C; SCHRECKENBERGER AB; STAEDT U; HEENE DL;
Indirizzi:
UNIV HEIDELBERG HOSP,KLINIKUM MANNHEIM,MED KLIN,THEODOR KUTZER UFER D-68135 MANNHEIM GERMANY UNIV HEIDELBERG,MED CLIN,FAC CLIN MED D-6800 MANNHEIM GERMANY INST CLIN PHARMACOL HOEHENKIRCHEN SIEGERTSBR GERMANY
Titolo Testata:
Journal of clinical pharmacology
fascicolo: 1, volume: 37, anno: 1997, supplemento:, S
pagine: 21 - 28
SICI:
0091-2700(1997)37:1<21:CMOHDP>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY-ARTERY DISEASE; THORACIC ELECTRICAL BIOIMPEDANCE; DIPYRIDAMOLE-ECHOCARDIOGRAPHY TEST; CARDIAC-OUTPUT ESTIMATION; M-MODE ECHOCARDIOGRAPHY; STROKE VOLUME; DOPPLER ECHOCARDIOGRAPHY; MYOCARDIAL-ISCHEMIA; HEALTHY-VOLUNTEERS; DOBUTAMINE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
33
Recensione:
Indirizzi per estratti:
Citazione:
A.W. Scherhag et al., "CONTINUOUS MEASUREMENT OF HEMODYNAMIC-ALTERATIONS DURING PHARMACOLOGICAL CARDIOVASCULAR STRESS USING AUTOMATED IMPEDANCE CARDIOGRAPHY", Journal of clinical pharmacology, 37(1), 1997, pp. 21-28

Abstract

The contribution of computerized impedance cardiography in monitoringand differentiating cardiovascular responses to pharmacologic stress after the administration of dipyridamole (group 1, n = 24) or dobutamine (group 2, n = 26) was investigated during stress echocardiography. Heart rate, stroke volume index, cardiac index and systemic vascular resistance index were evaluated continuously with an automated, computerized, signal-averaged impedance cardiography system. Dipyridamole hadlittle average effect on heart rate, stroke volume index, and cardiacindex. The responses were similar in patients with positive (n = 9) or negative (n = 15) stress echocardiography test results (as characterized by echocardiographic wall-motion abnormalities). Dobutamine induced a similar mean increase in heart rate in patients with negative (n = 13) or positive (n = 13) results on stress echocardiography. The mean increase in stroke volume index induced by dobutamine was greater inpatients with negative stress echocardiography test results than in patients with stress-induced wall-motion abnormalities. This distinction was also seen in the cardiac index; the mean change in patients withnegative stress echocardiography test results was larger than in patients with positive results. It is concluded that automated computerized impedance cardiography not only allows surveying and monitoring hemodynamic changes during pharmacologic stress echocardiography but also contributes to differentiation of pathologic stress responses.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 12/07/20 alle ore 03:19:26