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Titolo:
CHARACTERIZATION OF CYCLIC ADP-RIBOSE AND 2'-PHOSPHO-CYCLIC-ADP-RIBOSE BY P-31 NMR-SPECTROSCOPY
Autore:
SCHNACKERZ KD; VU CQ; GANI D; ALVAREZGONZALEZ R; JACOBSON MK;
Indirizzi:
UNIV WURZBURG,THEODOR BOVERI INST BIOWISSENSCH PHYSIOL CHEM 1,AM HUBLAND D-97074 WURZBURG GERMANY UNIV KENTUCKY,COLL PHARM,DIV MED CHEM & PHARMACEUT LEXINGTON KY 40536 UNIV KENTUCKY,LUCILLE P MARKEY CANC CTR LEXINGTON KY 40536 UNIV ST ANDREWS,SCH CHEM ST ANDREWS KY16 9ST FIFE SCOTLAND UNIV N TEXAS,DEPT MICROBIOL & IMMUNOL,HLTH SCI CTR FT WORTH TX 76107
Titolo Testata:
Bioorganic & medicinal chemistry letters
fascicolo: 5, volume: 7, anno: 1997,
pagine: 581 - 586
SICI:
0960-894X(1997)7:5<581:COCAA2>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
NUCLEAR MAGNETIC-RESONANCE; CELLS; PH;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
19
Recensione:
Indirizzi per estratti:
Citazione:
K.D. Schnackerz et al., "CHARACTERIZATION OF CYCLIC ADP-RIBOSE AND 2'-PHOSPHO-CYCLIC-ADP-RIBOSE BY P-31 NMR-SPECTROSCOPY", Bioorganic & medicinal chemistry letters, 7(5), 1997, pp. 581-586

Abstract

The P-31 NMR spectra of the Ca2+ mobilizing nucleotides cyclic ADP-ribose and 2'-phosphocyclic ADP-ribose have been studied. Both nucleotides show doublets of doublets in the range -9.5 to -11 ppm for the pyrophosphate group. The P-cADPR exhibits a singlet in the 0 to +4 ppm range for the 2'-phospho group. The pH dependence of the P-31 signals shows transitions with pK(a) values of 8.37 and 8.95 for cADPR and P-cADPR, respectively. (C) 1997 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/09/20 alle ore 03:14:51