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Titolo:
CARDIAC-ARRHYTHMIAS ON 24-H AMBULATORY ELECTROCARDIOGRAPHY IN OLDER WOMEN AND MEN - THE CARDIOVASCULAR HEALTH STUDY
Autore:
MANOLIO TA; FURBERG CD; RAUTAHARJU PM; SISCOVICK D; NEWMAN AB; BORHANI NO; GARDIN JM; TABATZNIK B;
Indirizzi:
NHLBI,DIV EPIDEMIOL & CLIN APPLICAT,FED BLDG,ROOM 301,7550 WISCONSIN AVE BETHESDA MD 20892 BOWMAN GRAY SCH MED,DEPT PUBL HLTH SCI WINSTON SALEM NC 00000 UNIV ALBERTA,EPICORE CTR EDMONTON AB CANADA UNIV WASHINGTON,DEPT BIOSTAT SEATTLE WA 98195 UNIV PITTSBURGH,GRAD SCH PUBL HLTH,DEPT EPIDEMIOL PITTSBURGH PA 00000 UNIV CALIF IRVINE,DEPT MED ORANGE CA 00000 JOHNS HOPKINS UNIV,SCH MED,DEPT MED BALTIMORE MD 21205
Titolo Testata:
Journal of the American College of Cardiology
fascicolo: 4, volume: 23, anno: 1994,
pagine: 916 - 925
SICI:
0735-1097(1994)23:4<916:CO2AEI>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
VENTRICULAR ECTOPIC ACTIVITY; ACUTE MYOCARDIAL-INFARCTION; ISCHEMIC-HEART-DISEASE; PROGNOSTIC-SIGNIFICANCE; PREMATURE BEATS; ELDERLY POPULATION; PREVALENCE; FREQUENT; MORTALITY; SURVIVORS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
40
Recensione:
Indirizzi per estratti:
Citazione:
T.A. Manolio et al., "CARDIAC-ARRHYTHMIAS ON 24-H AMBULATORY ELECTROCARDIOGRAPHY IN OLDER WOMEN AND MEN - THE CARDIOVASCULAR HEALTH STUDY", Journal of the American College of Cardiology, 23(4), 1994, pp. 916-925

Abstract

Objectives. This study describes the prevalence and correlates of cardiac arrhythmias in older persons. Background. Cardiac arrhythmias arefrequent in selected samples of elderly persons, but their prevalenceand association with cardiovascular disease and its risk factors havenot been examined in a large population based sample. Methods. In 1,372 participants in the Cardiovascular Health Study, a population-basedstudy of cardiovascular disease risk factors, 24-h ambulatory electrocardiography was performed. Results. Serious arrhythmias, such as sustained ventricular tachycardia and complete atrioventricular block, were uncommon, but brief episodes of ventricular tachycardia (greater than or equal to 3 consecutive ventricular depolarizations) were detectedin 4.3% of women and 10.3 % of men. Ventricular arrhythmias as a group (excluding ectopic beats <15/h) were more common in men than in women but were not significantly associated with age. The same patterns were true for bradycardia/conduction blocks. Supraventricular arrhythmias as a group (excluding ectopic beats <15/h), in contrast, did not differ by gender but were strongly associated with increased age. Multivariate analyses showed associations with arrhythmias to differ by gender, with only one association (increased age and supraventricular arrhythmias) present in both women and men. Ventricular arrhythmias, particularly in men, were associated with a higher prevalence of cardiovascular disease and its risk factors and with subclinical disease, as measured by increased left ventricular mass and impaired left ventricular function. Conclusions. Arrhythmias are common in the elderly, and their association with cardiovascular disease differs by gender. Although risk related to arrhythmias can only be determined by prospective study, such studies should have adequate power to examine potential genderdifferences in associations.

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Documento generato il 29/11/20 alle ore 16:03:05