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Titolo:
GENE-THERAPY - APPLICATIONS TO THE TREATMENT OF GASTROINTESTINAL AND LIVER-DISEASES
Autore:
CHANG AGY; WU GY;
Indirizzi:
UNIV CONNECTICUT,CTR HLTH,SCH MED,DEPT MED,DIV GASTROENTEROL HEPATOL,ROOM AM-044 FARMINGTON CT 06030 UNIV CONNECTICUT,CTR HLTH,SCH MED,DEPT MED,DIV GASTROENTEROL HEPATOL,ROOM AM-044 FARMINGTON CT 06030
Titolo Testata:
Gastroenterology
fascicolo: 4, volume: 106, anno: 1994,
pagine: 1076 - 1084
SICI:
0016-5085(1994)106:4<1076:G-ATTT>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
MICROCARRIER-ATTACHED HEPATOCYTES; GENETICALLY MODIFIED HEPATOCYTES; RECEPTOR-MEDIATED ENDOCYTOSIS; RAT HEPATOCYTES; HEPATOCELLULAR TRANSPLANTATION; DEFICIENT RABBITS; RETROVIRAL VECTOR; ENDOTHELIAL-CELLS; CYSTIC-FIBROSIS; HEMOPHILIA-B;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
121
Recensione:
Indirizzi per estratti:
Citazione:
A.G.Y. Chang e G.Y. Wu, "GENE-THERAPY - APPLICATIONS TO THE TREATMENT OF GASTROINTESTINAL AND LIVER-DISEASES", Gastroenterology, 106(4), 1994, pp. 1076-1084

Abstract

There has been much progress in our understanding of molecular mechanisms in the pathogenesis of inherited metabolic disorders. In addition, powerful new molecular techniques have made possible phenotypic alterations by delivery of foreign genes to target cells. As a result, concepts and methods that would have been considered purely science fiction 10 years ago can now be found in human clinical trials engaged in the treatment of these disorders. In this review, we have attempted to provide an introduction and survey of the topic of gene therapy, with specific examples of laboratory and clinical achievements to date, andhighlights on potentials for applications in digestive diseases.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/21 alle ore 14:54:10