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Titolo:
DESCRIPTION OF TIME-DOMAIN-BASED AND FREQUENCY-DOMAIN-BASED MEASURES OF HEART-RATE-VARIABILITY IN INDIVIDUALS TAKING ANTIARRHYTHMICS, BETA-BLOCKERS, CALCIUM-CHANNEL BLOCKERS, AND OR ANTIHYPERTENSIVE DRUGS AFTER SUDDEN CARDIAC-ARREST
Autore:
COWAN MJ; PIKE K; BURR RL; CAIN KC; NARAYANAN SB;
Indirizzi:
UNIV WASHINGTON,SCH NURSING,DEPT PHYSIOL NURSING,SM-27 SEATTLE WA 98195 UNIV WASHINGTON,SCH PUBL HLTH & COMMUNITY MED,DEPT BIOSTAT SEATTLE WA98195 UNIV WASHINGTON,COLL ENGN,DEPT ELECT ENGN SEATTLE WA 98195 UNIV WASHINGTON,SCH NURSING,DEPT PSYCHOSOCIAL NURSING SEATTLE WA 98195
Titolo Testata:
Journal of electrocardiology
, volume: 26, anno: 1993, supplemento:, S
pagine: 1 - 13
SICI:
0022-0736(1993)26:<1:DOTAFM>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
POWER SPECTRAL-ANALYSIS; ACUTE MYOCARDIAL-INFARCTION; PERIOD VARIABILITY; DEATH;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
25
Recensione:
Indirizzi per estratti:
Citazione:
M.J. Cowan et al., "DESCRIPTION OF TIME-DOMAIN-BASED AND FREQUENCY-DOMAIN-BASED MEASURES OF HEART-RATE-VARIABILITY IN INDIVIDUALS TAKING ANTIARRHYTHMICS, BETA-BLOCKERS, CALCIUM-CHANNEL BLOCKERS, AND OR ANTIHYPERTENSIVE DRUGS AFTER SUDDEN CARDIAC-ARREST", Journal of electrocardiology, 26, 1993, pp. 1-13

Abstract

Concomitant drug therapies after sudden cardiac arrest and their potential effect of altering heart rate variability (HRV) represent confounding factors in interpreting the outcome of nonpharmacologic therapies on HRV. The purpose of this study is to describe a broad spectrum oftime-domain and frequency-domain measurements of HRV in 50 individuals after sudden cardiac arrest. Some of the individuals were taking antiarrhythmics (n = 9), beta blockers (n = 13), calcium channel blockers(n = 10), nitrates (n = 8), cardiac glycosides (n = 10), and/or antihypertensives (n = 12). Heart rate variability was measured using a Holter recorder for 24 hours and the SpaceLabs FT2000 Monitoring System (Redmond, WA). In those individuals taking antiarrhythmic drugs, the power density within the low-frequency range (.016-.04 Hz) was significantly decreased (P = .001) compared to those not taking antiarrhythmics(n = 41). However, 78% of the people taking antiarrhythmics also had congestive heart failure (New York Heart Association functional classes II and III), which also decreased HRV. Those individuals taking betablockers tended to have slower heart rates (P < .01). The associationbetween beta blocker use and HRV was positive, but not statistically significant except for the increased power density in the low-frequency range (P < .05). In general, the relationships between HRV and drug therapy-calcium channel blockers, antihypertensives, cardiac glycosides, or nitrates-were not statistically significant.

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Documento generato il 11/07/20 alle ore 07:43:40