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Titolo:
BLOOD-PRESSURE VARIABILITY AND REFLEX CONTROL IN THE ELDERLY
Autore:
MANCIA G; DIRIENZO M; GRASSI G; PARATI G;
Indirizzi:
UNIV MILAN,ST GERARDO HOSP,CHAIR INTERNAL MED,VIA DONIZETTI 106 I-20052 MONZA ITALY
Titolo Testata:
Aging
fascicolo: 1, volume: 7, anno: 1995,
pagine: 3 - 9
SICI:
0394-9532(1995)7:1<3:BVARCI>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Keywords:
AGING; ARTERIAL BARORECEPTORS; BLOOD PRESSURE VARIABILITY; CARDIOPULMONARY RECEPTORS; SYMPATHETIC ACTIVITY;
Tipo documento:
Review
Natura:
Periodico
Citazioni:
NO
Recensione:
Indirizzi per estratti:
Citazione:
G. Mancia et al., "BLOOD-PRESSURE VARIABILITY AND REFLEX CONTROL IN THE ELDERLY", Aging, 7(1), 1995, pp. 3-9

Abstract

Several lines of experimental and clinical evidence collected over the past ten years suggest that the aging process is characterized not only by profound structural cardiovascular alterations, but also by marked functional changes in the reflex mechanisms involved in the homeostatic control of the circulation. This paper will examine how aging affects baroreceptor control of the heart and sympathetic nerve traffic,providing evidence that while the for mer is markedly impaired in theelderly, the latter is virtually preserved. It will also discuss the age-related alterations in cardiopulmonary receptor function that, under physiological conditions, tonically inhibit sympathetic vasoconstriction tone and renin release from the kidney. Finally, evidence will be provided showing that short- and long-term blood pres sure variabilities (and the different components of blood pressure variability) over24 hours undergo major changes in the elderly. All these alterations in neural cardiovascular control mechanisms have clearcut clinical implications representing a potential marker of the increased cardiovascular risk which characterizes elderly people.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 16:10:03