Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
FULMINANT-HEPATITIS FOLLOWING BONE-MARROW TRANSPLANTATION IN HEPATITIS-B VIRUS CARRIER SIBLINGS
Autore:
OMATA F; UENO F; KUSHIBIKI Y; TAKAHASHI H;
Indirizzi:
TOKAI UNIV,SCH MED,DEPT MED ISEHARA KANAGAWA 25911 JAPAN
Titolo Testata:
Journal of gastroenterology
fascicolo: 5, volume: 29, anno: 1994,
pagine: 653 - 655
SICI:
0944-1174(1994)29:5<653:FFBTIH>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Keywords:
FULMINANT HEPATITIS; INTERFERON-ALPHA; HEPATITIS-B VIRUS CARRIER; HEPATITIS-C VIRUS; BONE MARROW TRANSPLANTATION; CYCLOSPORINE-A;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
NO
Recensione:
Indirizzi per estratti:
Citazione:
F. Omata et al., "FULMINANT-HEPATITIS FOLLOWING BONE-MARROW TRANSPLANTATION IN HEPATITIS-B VIRUS CARRIER SIBLINGS", Journal of gastroenterology, 29(5), 1994, pp. 653-655

Abstract

A 19-year-old male healthy hepatitis B virus (HBV) carrier developed fulminant hepatitis following allogenic bone marrow transplantation (BMT) from his brother, who was also a healthy HBV carrier, during the first complete remission of acute myelogenic leukemia (M1, FAB classification). Serum markers related to both HBV and hepatitis C virus (HCV)were elevated during active liver injury when a point mutation in theprecore (pre-C) region occurred in the HBV. The patient received low-dose interferon alpha (IFN-alpha), while the dose of cyclosporin A wastapered; the patient eventually recovered from the liver injury. Fulminant hepatitis due to HBV and/or HCV following BMT is rare, and it isconsidered to have a very poor prognosis. The rationale for the use of low-dose IFN-alpha with cyclosporin A (CyA) is discussed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/09/20 alle ore 00:20:53