Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
MEMORY FOR SPATIAL LOCATION - FUNCTIONAL DISSOCIATION OF ENTORHINAL CORTEX AND HIPPOCAMPUS
Autore:
HUNT ME; KESNER RP; EVANS RB;
Indirizzi:
UNIV UTAH SALT LAKE CITY UT 00000 UNIV UTAH SALT LAKE CITY UT 00000
Titolo Testata:
Psychobiology
fascicolo: 3, volume: 22, anno: 1994,
pagine: 186 - 194
SICI:
0889-6313(1994)22:3<186:MFSL-F>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
WORKING-MEMORY; TRIPLE DISSOCIATION; IBOTENATE LESIONS; CAUDATE-NUCLEUS; FORNIX; PLACE; RATS; CONNECTIONS; COMPONENTS; SUBICULUM;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
33
Recensione:
Indirizzi per estratti:
Citazione:
M.E. Hunt et al., "MEMORY FOR SPATIAL LOCATION - FUNCTIONAL DISSOCIATION OF ENTORHINAL CORTEX AND HIPPOCAMPUS", Psychobiology, 22(3), 1994, pp. 186-194

Abstract

To test whether there is a functional dissociation between the hippocampus and entorhinal cortex, rats were trained on a variable spatial-location matching-to-sample (working memory) task with various delays. After training, rats with entorhinal cortex, entorhinal-cortex-plus-hippocampus/subiculum, hippocampus, control, or cortical control lesionswere tested for performance within the task. Results indicated that in the variable spatial-location condition relative to the control and cortical controls, all lesioned groups showed a profound impairment inperformance of the task across all delays. They were subsequently tested for acquisition of a constant spatial location task. In the constant spatial-location condition, the entorhinal cortex and entorhinal-cortex-plus-hippocampus/ subiculum lesioned groups did not learn the task, whereas the hippocampal lesioned group did. It is suggested that there is a functional dissociation between the hippocampus and the entorhinal cortex. It is proposed that the hippocampus encodes new spatial information within a working-memory system, whereas the entorhinal cortex represents spatial information within a reference-memory system aspart of a spatial cognitive map.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 10/07/20 alle ore 01:59:54