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Titolo:
NONHOMOLOGOUS RECOMBINATION BETWEEN THE HEMAGGLUTININ GENE AND THE NUCLEOPROTEIN GENE OF AN INFLUENZA-VIRUS
Autore:
ORLICH M; GOTTWALD H; ROTT R;
Indirizzi:
UNIV GIESSEN,INST VIROL,FRANKFURTER STR 107 D-35392 GIESSEN GERMANY
Titolo Testata:
Virology
fascicolo: 1, volume: 204, anno: 1994,
pagine: 462 - 465
SICI:
0042-6822(1994)204:1<462:NRBTHG>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
VIRAL-RNA; PATHOGENICITY; SEQUENCE;
Tipo documento:
Note
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
17
Recensione:
Indirizzi per estratti:
Citazione:
M. Orlich et al., "NONHOMOLOGOUS RECOMBINATION BETWEEN THE HEMAGGLUTININ GENE AND THE NUCLEOPROTEIN GENE OF AN INFLUENZA-VIRUS", Virology, 204(1), 1994, pp. 462-465

Abstract

Mutants of the influenza virus A/seal/Mass/1/80 (H7N7) are described which contain an insertion of 60 nucleotides in the hemagglutinin (HA)gene, derived most probably by recombination between the HA gene and the nucleoprotein gene of the same virus. The nonhomologous RNA recombination resulted in an enhanced hemagglutinin cleavability associated with broadening of the host cell spectrum, increased hemolytic activity, and increased pathogenicity for chickens. (C) 1994 Academic Press, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/01/20 alle ore 01:23:32