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Titolo:
THE SPECTRUM OF PATHOLOGICAL-CHANGES IN THE LUNG IN CHILDREN WITH THEACQUIRED-IMMUNODEFICIENCY-SYNDROME - AN AUTOPSY STUDY OF 36 CASES
Autore:
MORAN CA; SUSTER S; PAVLOVA Z; MULLICK FG; KOSS MN;
Indirizzi:
ARMED FORCES INST PATHOL,DEPT PULM & MEDIASTINAL PATHOL,RM 3017 WASHINGTON DC 20306 ARMED FORCES INST PATHOL,DEPT ENVIRONM PATHOL WASHINGTON DC 20306 MT SINAI MED CTR,DEPT PATHOL & LAB MED MIAMI FL 00000 UNIV MIAMI,SCH MED MIAMI FL 00000 UNIV SO CALIF,LOS ANGELES CTY MED CTR,WOMENS HOSP,DEPT PATHOL LOS ANGELES CA 90033
Titolo Testata:
Human pathology
fascicolo: 9, volume: 25, anno: 1994,
pagine: 877 - 882
SICI:
0046-8177(1994)25:9<877:TSOPIT>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
IMMUNE-DEFICIENCY SYNDROME; INFANTS; VIRUS; INFECTION; AIDS;
Keywords:
ACQUIRED IMMUNODEFICIENCY SYNDROME; CHILDREN; PULMONARY MANIFESTATIONS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
15
Recensione:
Indirizzi per estratti:
Citazione:
C.A. Moran et al., "THE SPECTRUM OF PATHOLOGICAL-CHANGES IN THE LUNG IN CHILDREN WITH THEACQUIRED-IMMUNODEFICIENCY-SYNDROME - AN AUTOPSY STUDY OF 36 CASES", Human pathology, 25(9), 1994, pp. 877-882

Abstract

We present the pulmonary findings in 36 autopsies of children affected by the acquired immunodeficiency syndrome (AIDS). Twenty-three patients were male and 13 were female, ranging in age between 3 days and 13years. Twenty children had human immunodeficiency virus (HIV)-positive parents or parents who were at high risk of exposure (intravenous drug abusers and prostitutes), five had a history of transfusion, and one had a history of renal transplantation and blood transfusion. Clinically, the patients presented with recurrent infections, failure to thrive, hepatosplenomegaly, fever, cough, and/or hemoptysis. Histologically, specific infectious processes were the most common finding (75% ofcases), with Pneumocystis carinii pneumonia being the most prevalent type of infection, followed by bacterial pneumonia. Neoplastic conditions and lymphoid interstitial pneumonia were less frequent (approximately 10% of cases). In addition, in approximately 10% of the cases the pulmonary findings were non-specific (ie, pulmonary edema and atelectasis) and probably unrelated to HIV infection. Our findings suggest that specific infectious conditions constitute the most common type of pulmonary pathology in children with AIDS. However, because there is a small percentage of children with nonspecific finding, a transbronchialbiopsy is important for proper evaluation before institution of therapy. HUM PATHOL 25:877-882. This is a US government work. There are no restrictions on its use.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 10/07/20 alle ore 11:51:37