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Titolo:
TRYPSIN-LIKE ACTIVITY LEVELS OF TREPONEMA-DENTICOLA AND PORPHYROMONAS-GINGIVALIS IN ADULTS WITH PERIODONTITIS
Autore:
PEDERSON ED; MILLER JW; MATHESON S; SIMONSON LG; CHADWICK DE; COVILL PJ; TURNER DW; LAMBERTS BL; MORTON HE;
Indirizzi:
USN,DENT RES INST,DIV IMMUNOL,BLDG 1-H GREAT LAKES IL 60088 USN,MED RES & DEV COMMAND,LAB A BETHESDA MD 00000 NORTHWESTERN UNIV,SCH DENT CHICAGO IL 60611 DENTSPLY INT YORK PA 00000
Titolo Testata:
Journal of clinical periodontology
fascicolo: 8, volume: 21, anno: 1994,
pagine: 519 - 525
SICI:
0303-6979(1994)21:8<519:TALOTA>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
DL-ARGININE-NAPHTHYLAMIDE; API-ZYM SYSTEM; BACTEROIDES-GINGIVALIS; CREVICULAR FLUID; MONOCLONAL-ANTIBODIES; SUBGINGIVAL PLAQUE; BACTERIA; DISEASE; BANA; PERIODONTOPATHOGENS;
Keywords:
TRYPSIN-LIKE ACTIVITY; TREPONEMA DENTICOLA; PORPHYROMONAS GINGIVALIS; PERIODONTITIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
33
Recensione:
Indirizzi per estratti:
Citazione:
E.D. Pederson et al., "TRYPSIN-LIKE ACTIVITY LEVELS OF TREPONEMA-DENTICOLA AND PORPHYROMONAS-GINGIVALIS IN ADULTS WITH PERIODONTITIS", Journal of clinical periodontology, 21(8), 1994, pp. 519-525

Abstract

Treponema denticola (Td) and Porphyromonas gingivalis (Pg) are associated with human moderate and severe adult periodontal diseases. This study quantifies these two anaerobes and their trypsin-like (TL) activities in subgingival plaque collected from both clinically healthy and periodontally diseased sites of human periodontitis patients. Antigen levels of the microorganisms were determined by monoclonal antibodies and TL activities were measured by the fluorescent substrate Z-gly-gly-arg-AFC in a disc format. Significant positive correlations were observed between the antigen levels and the TL activities when the data were subjected to statistical analyses both on a site-specific and on a patient basis. Anaerobe synergism was found between Td and Pg in a continental US population, and positive correlations were found between anaerobe levels (individually and total) and clinical indicators of adult periodontitis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/11/20 alle ore 21:56:52