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Titolo:
SWISS POPULATION-DATA ON 3 TETRAMERIC SHORT TANDEM REPEAT LOCI - VWA,HUMTHO1, AND F13A1 - DERIVED USING MULTIPLEX PCR AND LASER FLUORESCENCE DETECTION
Autore:
HOCHMEISTER MN; JUNG JM; BUDOWLE B; BORER UV; DIRNHOFER R;
Indirizzi:
UNIV BERN,INST RECHTS MED,DEPT FORENS MED,BUHLSTR 20 CH-3012 BERN SWITZERLAND FED BUR INVEST ACAD,CTR FORENS SCI RES & TRAINING QUANTICO VA 22135
Titolo Testata:
International journal of legal medicine
fascicolo: 1, volume: 107, anno: 1994,
pagine: 34 - 36
SICI:
0937-9827(1994)107:1<34:SPO3TS>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
GENETIC-VARIATION; GENOMIC DNA; HETEROZYGOSITY; AMPLIFICATION; POLYMORPHISM; DISTANCE; ALLELES;
Keywords:
PCR; MULTIPLEX; VWA; HUMTHO1; F13A1; FLUORESCENCE DETECTION; HARDY-WEINBERG EXPECTATIONS; SHORT TANDEM REPEAT LOCI;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
20
Recensione:
Indirizzi per estratti:
Citazione:
M.N. Hochmeister et al., "SWISS POPULATION-DATA ON 3 TETRAMERIC SHORT TANDEM REPEAT LOCI - VWA,HUMTHO1, AND F13A1 - DERIVED USING MULTIPLEX PCR AND LASER FLUORESCENCE DETECTION", International journal of legal medicine, 107(1), 1994, pp. 34-36

Abstract

Allele and genotype frequencies for 3 tetrameric short tandem repeat loci VWA, HUMTHO1, and F13A1 were determined in a Swiss population sample using multiplex PCR and subsequent electrophoresis in DNA sequencing gels processed by automated laser fluorescence detection. The technique allows single base pair resolution and rapid typing, with a concomitant reduction in the potential for human transcriptional typing errors. All loci meet Hardy-Weinberg expectations. In addition, there is little evidence for association of alleles among the 3 loci. The allelic frequency data can be used in forensic analyses and paternity teststo estimate the frequency of a multiple STR locus DNA profile in the Swiss population.

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Documento generato il 30/11/20 alle ore 10:19:25