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Titolo:
CAFFEINE-INDUCED HYPERCALCIURIA AND RENAL PROSTAGLANDINS - EFFECT OF ASPIRIN AND N-3 POLYUNSATURATED FATTY-ACIDS
Autore:
MORGAN LJ; LIEBMAN M; BROUGHTON KS;
Indirizzi:
UNIV WYOMING,DEPT HOME ECON NUTR,BOX 3354 UNIV STN LARAMIE WY 82071 UNIV WYOMING,DEPT HOME ECON NUTR LARAMIE WY 82071
Titolo Testata:
The American journal of clinical nutrition
fascicolo: 3, volume: 60, anno: 1994,
pagine: 362 - 368
SICI:
0002-9165(1994)60:3<362:CHARP->2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
URINARY CALCIUM EXCRETION; DIETARY CAFFEINE; HEALTHY-VOLUNTEERS; WOMEN; RAT; THEOPHYLLINE; PHOSPHORUS; INHIBITION; MAGNESIUM; PREMENOPAUSAL;
Keywords:
CAFFEINE; HYPERCALCIURIA; ASPIRIN; RENAL PROSTAGLANDINS; FISH OIL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
47
Recensione:
Indirizzi per estratti:
Citazione:
L.J. Morgan et al., "CAFFEINE-INDUCED HYPERCALCIURIA AND RENAL PROSTAGLANDINS - EFFECT OF ASPIRIN AND N-3 POLYUNSATURATED FATTY-ACIDS", The American journal of clinical nutrition, 60(3), 1994, pp. 362-368

Abstract

Effects of aspirin and fish-oil ingestion on caffeine-induced hypercalciuria and renal prostaglandins (PG) were investigated in 12 healthy women. The 11-wk study consisted of 7-d baseline, 5-d aspirin (1000 mg/d), 11-d washout, and two 24-d fish-oil periods (FO-1 and FO-2, respectively, providing 1.5 vs 3.0 g n-3 fatty acids/d) separated by a 4-d washout period. Caffeine-load (CL) tests providing 5 mg caffeine/kg body wt were administered after baseline and each experimental period. Timed urine samples were collected precaffeine (basal) and at 1, 2, and3 h post-caffeine. PGE(2) excretion decreased during tests after aspirin and FO-2. There were significant increases in PG(2 alpha) from baseline during each CL test. Hypercalciuria was observed during each CL test and the magnitude of this response was not altered by the experimental treatments. The finding that concentrations of post-caffeine urinary PGF(2 alpha) paralleled concentrations of urinary calcium supports the possibility that this prostaglandin plays a role in caffeine-induced hypercalciuria.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 16:31:19