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Titolo:
PERTUSSIS SEROPREVALENCE IN EMERGENCY DEPARTMENT STAFF
Autore:
WRIGHT SW; EDWARDS KM; DECKER MD; LAMBERTH MM;
Indirizzi:
VANDERBILT UNIV,MED CTR,DEPT EMERGENCY MED,240 MED CTR S NASHVILLE TN37212
Titolo Testata:
Annals of emergency medicine
fascicolo: 3, volume: 24, anno: 1994,
pagine: 413 - 417
SICI:
0196-0644(1994)24:3<413:PSIEDS>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
NO
Recensione:
Indirizzi per estratti:
Citazione:
S.W. Wright et al., "PERTUSSIS SEROPREVALENCE IN EMERGENCY DEPARTMENT STAFF", Annals of emergency medicine, 24(3), 1994, pp. 413-417

Abstract

Study objective: The purpose of this study was to look at the prevalence of pertussis immunity in emergency department employees. Design: Prospective, observational study conducted in September 1992. Setting: A university hospital ED. Participants: A convenience sample of 73 ED employees. Interventions: Blood was collected from ED staff and assayed for antibody to pertussis toxin and filamentous hemagglutinin. Results: Ninety-nine percent of the subjects reported childhood immunization. Geometric mean titers were 3.6 (geometric SD, 3.2) enzyme-linked immunosorbent assay (ELISA) units for pertussis toxin and 12.1 (geometric SD, 3.3) ELISA units for filamentous hemagglutinin. These titers arecomparable to those previously reported in other adults not immunizedsince childhood and are substantially lower than the levels commonly seen in children or adults following immunization. Titers did not differ significantly between male and female subjects or between subjects with or without a recent prolonged cough, family members with a cough,or small children in the household. Conclusion: Most ED staff membershave low levels of antibody to pertussis and may be at risk for acquiring the disease from infected children or adults, with subsequent risk of transmission to susceptible patients. Booster immunization with an acellular pertussis vaccine has been shown to be safe and immunogenic in adults and may be appropriate for adult ED personnel to reduce these risks.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 11/07/20 alle ore 21:03:08