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Titolo:
A NEW NONIONIC MACROCYCLIC GADOLINIUM(III) CHELATE AS A POTENTIAL MAGNETIC-RESONANCE-IMAGING CONTRAST AGENT
Autore:
INOUE MB; ORAM P; INOUE M; FERNANDO Q; ALEXANDER AL; UNGER EC;
Indirizzi:
UNIV SONORA,CPIM,APARTADO POSTAL 130 SONORA MEXICO UNIV SONORA,CPIM SONORA MEXICO
Titolo Testata:
Magnetic resonance imaging
fascicolo: 3, volume: 12, anno: 1994,
pagine: 429 - 432
SICI:
0730-725X(1994)12:3<429:ANNMGC>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Keywords:
MRI CONTRAST AGENT; NONIONIC GADOLINIUM CHELATE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
NO
Recensione:
Indirizzi per estratti:
Citazione:
M.B. Inoue et al., "A NEW NONIONIC MACROCYCLIC GADOLINIUM(III) CHELATE AS A POTENTIAL MAGNETIC-RESONANCE-IMAGING CONTRAST AGENT", Magnetic resonance imaging, 12(3), 1994, pp. 429-432

Abstract

A new Gd-III complex of a 17-membered macrocycle with three pendant carboxymethyl groups has been synthesized; the ligand has been obtainedin a single step from diethylenetriaminepentaacetic dianhydride (pentetic dianhydride) and 1,4-butanediamine (putrescine). An X-ray crystalanalysis has shown that the complex is a nonionic metal chelate with a coordinated water molecule. The near-zero electrical conductivity, 1Omega(-1) cm(2) mol-l, of a 1 mM solution indicated that the metal chelate is essentially undissociated. The NMR TI relaxivity is 2.5 s(-1)mM(-1) at a resonance field of 64 MHz, and 3.4 s(-1) mM(-1) at 250 MHz. This new Gd-III complex is a potentially important magnetic resonance imaging contrast agent.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/09/20 alle ore 11:39:05