Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
CLINICAL-EVALUATION OF NUCLEAR-MATRIX-PROTEIN-22 (NMP22) IN URINE AS A NOVEL MARKER FOR UROTHELIAL CANCER
Autore:
MIYANAGA N; AKAZA H; ISHIKAWA S; OHTANI M; NOGUCHI R; KAWAI K; KOISO K; KOBAYASHI M; KOYAMA A; TAKAHASHI T;
Indirizzi:
UNIV TSUKUBA,INST CLIN MED,DEPT UROL,1-1-1 TEN NODAI TSUKUBA IBARAKI 305 JAPAN UNIV TSUKUBA,INST CLIN MED,DEPT INTERNAL MED TSUKUBA IBARAKI 305 JAPAN IBARAKI NMP RES COMM TSUKUBA IBARAKI JAPAN KONICA CORP HINO TOKYO JAPAN
Titolo Testata:
European urology
fascicolo: 2, volume: 31, anno: 1997,
pagine: 163 - 168
SICI:
0302-2838(1997)31:2<163:CON(IU>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
TRANSITIONAL CELL-CARCINOMA; FLOW-CYTOMETRY; BLADDER-CANCER; FOLLOW-UP; CYTOLOGY;
Keywords:
NMP22; URINE MARKER; UROTHELIAL CANCER; TUMOR RECURRENCE; APOPTOSIS; VOIDED-URINE CYTOLOGY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
21
Recensione:
Indirizzi per estratti:
Citazione:
N. Miyanaga et al., "CLINICAL-EVALUATION OF NUCLEAR-MATRIX-PROTEIN-22 (NMP22) IN URINE AS A NOVEL MARKER FOR UROTHELIAL CANCER", European urology, 31(2), 1997, pp. 163-168

Abstract

Objectives: This study was undertaken to determine the clinical usefulness of nuclear matrix protein 22 (NMP22) as a novel urine marker forurothelial cancer, particularly, to substitute for voided-urine cytology. Methods: NMP22 values were determined for 280 patients and 20 healthy volunteers by NMP22 Test Kit based on an enzyme-linked immunosorbent assay. Results: When the cut-off value was set at 10 U/ml, the positive rate of urinary NMP22 for urothelial cancer was 80.9% (38/47), whereas that for posttreatment cases and benign diseases was 35.7% (74/207). When urinary NMP22 and voided-urine cytology were compared, the test for urinary NMP22 showed higher sensitivity than cytology in patients with urothelial cancer. When urinary NMP22 values were determinedpre- and postoperatively in patients with urothelial cancer, the postoperative value decreased in all patients, and were below the cut-off value in all except one patient. Conclusions: Urinary NMP22 is a useful diagnostic marker as a substitute for voided-urine cytology for the surveillance of urothelial cancer.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 15:03:38