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Titolo:
BONE-MINERAL DENSITY OF TOTAL-BODY, SPINE, AND FEMORAL-NECK IN CHILDREN AND YOUNG-ADULTS - A CROSS-SECTIONAL AND LONGITUDINAL-STUDY
Autore:
LU PW; BRIODY JN; OGLE GD; MORLEY K; HUMPHRIES IRJ; ALLEN J; HOWMANGILES R; SILLENCE D; COWELL CT;
Indirizzi:
ROYAL ALEXANDRA HOSP CHILDREN,ROBERT VINES GROWTH RES CTR SYDNEY NSW 2050 AUSTRALIA ROYAL ALEXANDRA HOSP CHILDREN,DEPT NUCL MED SYDNEY NSW AUSTRALIA ROYAL ALEXANDRA HOSP CHILDREN,DEPT MED GENET SYDNEY NSW AUSTRALIA ROYAL ALEXANDRA HOSP CHILDREN,JAMES FAIRFAX INST PAEDIAT CLIN NUTR SYDNEY NSW AUSTRALIA
Titolo Testata:
Journal of bone and mineral research
fascicolo: 9, volume: 9, anno: 1994,
pagine: 1451 - 1458
SICI:
0884-0431(1994)9:9<1451:BDOTSA>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
X-RAY ABSORPTIOMETRY; LUMBAR SPINE; PHOTON-ABSORPTIOMETRY; MASS; GROWTH; DETERMINANTS; PUBERTY; WOMEN; AGE; FEMALES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
21
Recensione:
Indirizzi per estratti:
Citazione:
P.W. Lu et al., "BONE-MINERAL DENSITY OF TOTAL-BODY, SPINE, AND FEMORAL-NECK IN CHILDREN AND YOUNG-ADULTS - A CROSS-SECTIONAL AND LONGITUDINAL-STUDY", Journal of bone and mineral research, 9(9), 1994, pp. 1451-1458

Abstract

Bone mineral density (BMD) of total body (TBMD), lumbar spine (L2-4),and femoral neck was measured in 266 normal subjects (136 males) aged4-27 years (mean 13 years) using dual-energy x-ray absorptiometry (DXA). BMD of all sites increased significantly with age until 17.5 yearsin males and 15.8 years in females, except for femoral neck BMD in females, which peaked at age 14.1 years. Males had higher peak TBMD, which was attributed to greater weight and lean tissue mass. In contrast,despite a later timing, peak L2-4 BMD in males was not different fromthat in females. Before peak BMD, weight was the best predictor of TBMD and L2-4 BMD in both sexes (r(2) ranged from 0.77 to 0.88), whereasfemoral neck BMD was predicted equally by height and weight. Longitudinal information collected from 53 (25 boys) of these children, aged 4-16.9 years, showed that the average annualized gain in TBMD was 0.047g/cm(2) for boys and 0.039 g/cm(2) for girls. No significant difference in the association between age and BMD (slopes) was found between cross-sectional and longitudinal data for either sex. We conclude that the timing for peak BMD was consistent for total body, lumbar spine, and femoral neck for each sex. The earlier peak BMD in females is most likely related to earlier puberty. The cross-sectional normative data of this study are useful in serving as a standard for serial assessment in health and disease states.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 02:11:39