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Titolo:
RISK-FACTORS FOR CALCULUS FORMATION IN PATIENTS WITH RENAL-TRANSPLANTS
Autore:
HARPER JM; SAMUELL CT; HALLSON PC; WOOD SM; MANSELL MA;
Indirizzi:
MIDDLESEX HOSP,DEPT NEPHROL,MORTIMER ST LONDON W1N 8AA ENGLAND MIDDLESEX HOSP,DEPT NEPHROL LONDON W1N 8AA ENGLAND ST PETERS HOSP,DEPT NEPHROL LONDON WC2A 2EX ENGLAND ST PETERS HOSP,DEPT CHEM PATHOL LONDON WC2A 2EX ENGLAND MIDDLESEX HOSP,DEPT CHEM PATHOL LONDON ENGLAND
Titolo Testata:
British Journal of Urology
fascicolo: 2, volume: 74, anno: 1994,
pagine: 147 - 150
SICI:
0007-1331(1994)74:2<147:RFCFIP>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
LITHIASIS; URATE; FLOW;
Keywords:
RENAL CALCULI; RENAL TRANSPLANT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
21
Recensione:
Indirizzi per estratti:
Citazione:
J.M. Harper et al., "RISK-FACTORS FOR CALCULUS FORMATION IN PATIENTS WITH RENAL-TRANSPLANTS", British Journal of Urology, 74(2), 1994, pp. 147-150

Abstract

Objective To investigate the risk factors for stone formation in patients with functioning renal transplants in whom renal calculi develop. Patients and methods Renal calculi developed in six of 178 patients with functioning renal transplants under current review, an incidence of 3%. Risk factors for stone formation were investigated in five of these patients and compared with a randomly selected control group of 41transplant patients with no stone problems. Results Patients with transplant calculi typically passed smaller volumes of significantly moreconcentrated and alkaline urine with greater urinary excretion of uric acid (P<0.05). Urine calcium excretion was also increased. Crystalluria was present in three of five stone formers compared with two of 25controls. Overall, metabolic abnormalities included hypocitraturia (75%), hyperparathyroidism (36%), hypophosphataemia (24%) and hypercalcaemia (10%). Urinary infection was common (50%) and urinary output of magnesium and phosphate was at the lower end of normal for all patients. Conclusion These results suggest a multifactorial aetiology for stone formation in renal transplant recipients. Approaches to prevention and management are discussed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 02:12:50