Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
COMPARISON OF VESPULA-GERMANICA VENOMS OBTAINED FROM DIFFERENT SOURCES
Autore:
SANCHEZ F; BLANCA M; MIRANDA A; CARMONA MJ; GARCIA J; FERNANDEZ J; TORRES MJ; RONDON MC; JUAREZ C;
Indirizzi:
CARLOS HAYA HOSP,DEPT INTERNAL MED,ALLERG DIS RES UNIT E-29011 MALAGASPAIN CARLOS HAYA HOSP,DEPT INTERNAL MED,ALLERG DIS RES UNIT E-29011 MALAGASPAIN HOSP ELCHE,ALLERGY UNIT ALACANT SPAIN
Titolo Testata:
International archives of allergy and immunology
fascicolo: 4, volume: 104, anno: 1994,
pagine: 385 - 389
SICI:
1018-2438(1994)104:4<385:COVVOF>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
HYMENOPTERA VENOMS; POLISTES-DOMINULUS; HONEYBEE VENOM; IGE ANTIBODIES; IMMUNOTHERAPY; ALLERGY; QUANTITATION; DIAGNOSIS; PROTEIN; VESPIDS;
Keywords:
IGE ANTIBODIES; VESPULA GERMANICA VENOMS; COMPARATIVE STUDIES; VESPULA SPECIES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
36
Recensione:
Indirizzi per estratti:
Citazione:
F. Sanchez et al., "COMPARISON OF VESPULA-GERMANICA VENOMS OBTAINED FROM DIFFERENT SOURCES", International archives of allergy and immunology, 104(4), 1994, pp. 385-389

Abstract

This study was carried out to compare the allergenic potency of Vespula germanica (VG) venoms extracted by different methods and commercially available venoms from Vespula species currently used for in vivo and in vitro studies including immunotherapy. Pure VG venom was used as the reference material. Protein content and enzymatic and allergenic properties of all venoms studied were determined by dye stain reagent, hyaluronidase and phospholipase A(1)B enzyme activities, and radioallergosorbent test inhibition studies, respectively. Radioallergosorbent test discs sensitized with commercial and pure VG venom were compared using specific IgE antibodies from subjects allergic to VG venom. The data obtained indicate that there were important differences in the allergenic potency between the Vespula species venoms employed for in vivo and/or in vitro assays, VG venom obtained by sac dissection, and pure VG venom. These results indicate that venoms from Vespula species used for in vitro and in vivo tests have a lower concentration of allergens and contain nonvenom proteins. These data should be taken into account when these vespid venoms are used for diagnostic purposes and also when evaluating immunotherapy studies.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/12/20 alle ore 20:09:23