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Titolo:
INVASIVE DISEASE CAUSED BY NEISSERIA-MENINGITIDIS RELATIVELY RESISTANT TO PENICILLIN IN NORTH-CAROLINA
Autore:
WOODS CR; SMITH AL; WASILAUSKAS BL; CAMPOS J; GIVNER LB;
Indirizzi:
WAKE FOREST UNIV,BOWMAN GRAY SCH MED,DEPT PEDIAT,MED CTR BLVD,300 S HAWTHORNE RD WINSTON SALEM NC 27157 WAKE FOREST UNIV,BOWMAN GRAY SCH MED,DEPT PATHOL WINSTON SALEM NC 27103 UNIV WASHINGTON,SCH MED,DEPT PEDIAT SEATTLE WA 98195 CTR NACL MICROBIOL VIROL & INMUNOL SANITARIAS MAJADAHONDA,INST SALUD CARLOS 3,DEPT DIAGNOST MADRID SPAIN
Titolo Testata:
The Journal of infectious diseases
fascicolo: 2, volume: 170, anno: 1994,
pagine: 453 - 456
SICI:
0022-1899(1994)170:2<453:IDCBNR>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
GENETIC DIVERSITY; MENINGOCOCCI; INFECTIONS; SPAIN;
Tipo documento:
Note
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
16
Recensione:
Indirizzi per estratti:
Citazione:
C.R. Woods et al., "INVASIVE DISEASE CAUSED BY NEISSERIA-MENINGITIDIS RELATIVELY RESISTANT TO PENICILLIN IN NORTH-CAROLINA", The Journal of infectious diseases, 170(2), 1994, pp. 453-456

Abstract

A case of sepsis and meningitis caused by Neisseria meningitidis withrelative resistance to penicillin occurred in North Carolina in August 1992. This isolate was relatively resistant due to decreased affinity of its penicillin-binding protein 2 for penicillin. Such isolates have been reported in Spain, elsewhere in Europe, in South Africa, and in Canada, but invasive disease caused by meningococcal isolates relatively resistant to penicillin was not recognized in the United States before a preliminary report of this case in October 1992. The Centers for Disease Control and Prevention recently retrospectively identified 3 additional cases from 1991. A fifth case occurred in Kentucky in 1993. Surveillance studies of penicillin susceptibility of N. meningitidis isolates suggest such meningococci have existed sporadically in the past. Increases in prevalence and magnitude of penicillin resistance among strains of N. meningitidis would require reconsideration of current clinical practice with regard to treatment of meningococcal disease.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/12/20 alle ore 04:56:58