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Titolo:
OVARIAN-TUMORS - PREDICTION OF THE PROBABILITY OF MALIGNANCY BY USINGPATIENTS AGE AND TUMOR MORPHOLOGIC FEATURES WITH A LOGISTIC MODEL
Autore:
MINARETZIS D; TSIONOU C; TZIORTZIOTIS D; MICHALAS S; ARAVANTINOS D;
Indirizzi:
HARVARD UNIV,BETH ISRAEL HOSP,SCH MED,DEPT OBSTET & GYNECOL,DA 882,330 BROOKLINE AVE BOSTON MA 02215 UNIV ATHENS,ALEXANDRA MATERN HOSP,DEPT OBSTET & GYNECOL ATHENS GREECE
Titolo Testata:
Gynecologic and obstetric investigation
fascicolo: 2, volume: 38, anno: 1994,
pagine: 140 - 144
SICI:
0378-7346(1994)38:2<140:O-POTP>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
SERUM CA-125 LEVELS; CANCER; ULTRASOUND; BENIGN; RISK;
Keywords:
OVARIAN NEOPLASM; OVARIAN CANCER; EPIDEMIOLOGY; PREDICTION OF MALIGNANCY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
22
Recensione:
Indirizzi per estratti:
Citazione:
D. Minaretzis et al., "OVARIAN-TUMORS - PREDICTION OF THE PROBABILITY OF MALIGNANCY BY USINGPATIENTS AGE AND TUMOR MORPHOLOGIC FEATURES WITH A LOGISTIC MODEL", Gynecologic and obstetric investigation, 38(2), 1994, pp. 140-144

Abstract

An attempt was made to predict the probability of malignancy of a given ovarian tumor in a certain patient by using the age and simple morphologic features of the tumor. A cohort of 959 patients with ovarian tumors was analysed retrospectively according to the patient's age and tumor characteristics such as greatest diameter, consistency, bilaterality and diagnosis as malignant (271 patients) or benign (688 patients). All variables were entered unconditionally in a logistic regression. The presence of solid/multilocular elements has a 9.6-fold increasedrisk of malignancy, where a bilateral tumor has a 2.8-fold increase. Significant increase in risk of malignancy was observed in ages under 20 and over 40 years, as well as in tumors with a diameter larger than9 cm. All variables were highly significant associated with the discrimination between benign and malignant. A formula including all variables has been developed so that the probability of malignancy can be estimated by a scientific calculator. In conclusion, simple, easily determined by ultrasound and reproducible criteria such as patient's age, tumor size, consistency and bilaterality were assembled in a logistic model in order to predict the probability of malignancy for a given ovarian tumor, in an individual patient.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/04/20 alle ore 20:20:04