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Titolo:
EFFECT OF AGING ON URINARY-EXCRETION OF 18-HYDROXYCORTISOL
Autore:
TAKEDA Y; MIYAMORI I; YONEDA T; IKI K; HATAKEYAMA H; TAKEDA R;
Indirizzi:
KANAZAWA UNIV,SCH MED,DEPT INTERNAL MED 2,13-1 TAKARA MACHI KANAZAWA 920 JAPAN
Titolo Testata:
Journal of steroid biochemistry and molecular biology
fascicolo: 3-4, volume: 50, anno: 1994,
pagine: 167 - 168
SICI:
0960-0760(1994)50:3-4<167:EOAOUO>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
ALDOSTERONE SYNTHASE CYTOCHROME-P-450; MINERALOCORTICOIDS; 19-NORALDOSTERONE; SYSTEM;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
13
Recensione:
Indirizzi per estratti:
Citazione:
Y. Takeda et al., "EFFECT OF AGING ON URINARY-EXCRETION OF 18-HYDROXYCORTISOL", Journal of steroid biochemistry and molecular biology, 50(3-4), 1994, pp. 167-168

Abstract

The secretion of aldosterone declines with age. We reported that sodium depletion increased urinary excretion of 18-hydroxycortisol (18-OH-F). To elucidate the effect of aging on urinary excretion of 18-OH-F, we measured urinary 18-OH-F in 30 normotensive subjects aged 20-70 yr. There were significant negative correlations between age and urinary excretion of 18-OH-F or of aldosterone (r = -0.49, r = -0.58, P < 0.05, respectively) but not of urinary free cortisol. These results suggest that angiotensin may contribute to chronic regulation of 18-OH-F.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 14:20:17