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Titolo:
AORTIC BARORECEPTORS PLAY A PREDOMINANT ROLE IN THE REGULATION OF HINDLIMB VASCULAR-RESISTANCE IN RATS
Autore:
MACHADO BH; BONAGAMBA LGH; CASTANIA JA; MENANI JV;
Indirizzi:
UNIV SAO PAULO,SCH MED,DEPT PHYSIOL BR-14049 RIBEIRAO PRET SP BRAZIL PAULISTA STATE UNIV,SCH DENT,DEPT PHYSIOL BR-14801903 SAO PAULO BRAZIL
Titolo Testata:
The American journal of physiology
fascicolo: 2, volume: 267, anno: 1994,
parte:, 2
pagine: 180000476 - 180000480
SICI:
0002-9513(1994)267:2<180000476:ABPAPR>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
CONSCIOUS RATS; REFLEX; OCCLUSION; NEURONS;
Keywords:
CARDIOVASCULAR REGULATION; BLOOD FLOW; BAROREFLEX; CAROTID BARORECEPTORS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
16
Recensione:
Indirizzi per estratti:
Citazione:
B.H. Machado et al., "AORTIC BARORECEPTORS PLAY A PREDOMINANT ROLE IN THE REGULATION OF HINDLIMB VASCULAR-RESISTANCE IN RATS", The American journal of physiology, 267(2), 1994, pp. 180000476-180000480

Abstract

In previous studies using bilateral carotid occlusion in conscious freely moving rats we suggested that aortic baroreceptors may play a more important role in the regulation of hindlimb than in renal and mesenteric vascular resistances. In the present study we performed electrical stimulation of the aortic baroreceptor nerve and analyzed the changes in mean arterial pressure and in hindlimb, renal, and mesenteric vascular resistances. All the experiments were performed under urethan anesthesia. Unilateral electrical stimulation (3 V, 2 ms, 50 Hz) of theaortic baroreceptor nerve produced a fall in arterial pressure (-27 +/- 3 mmHg) and an important reduction in hindlimb vascular resistance (-43 +/- 5%), with an increase in renal (+3 +/- 14%) and mesenteric (+48 +/- 12%) vascular resistances. Similar changes in arterial pressureas well as in the resistance of the three vascular beds studied were also observed during electrical stimulation of the aortic baroreceptornerve in rats with bilateral carotid baroreceptor denervation or in rats treated with methylatropine. The data obtained with electrical stimulation indicated that aortic baroreceptors play a more important role in the regulation of blood flow in hindlimb than in renal and mesenteric vascular beds.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 11/07/20 alle ore 03:19:22