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Titolo:
CHARACTERIZATION OF AUSTRALIAN OVINE ADENOVIRUS ISOLATES
Autore:
BOYLE DB; PYE AD; KOCHERHANS R; ADAIR BM; VRATI S; BOTH GW;
Indirizzi:
CSIRO,DIV ANIM HLTH,AUSTRALIAN ANIM HLTH LAB,POB 24 GEELONG VIC 3220 AUSTRALIA DEPT AGR,DIV VET SCI STORMONT NORTH IRELAND CSIRO,DIV BIOMOLEC ENGN N RYDE NSW 2113 AUSTRALIA
Titolo Testata:
Veterinary microbiology
fascicolo: 3, volume: 41, anno: 1994,
pagine: 281 - 291
SICI:
0378-1135(1994)41:3<281:COAOAI>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
PASTEURELLA-HAEMOLYTICA; EXPERIMENTAL-INFECTION; LAMBS; SHEEP; IDENTIFICATION; EXPRESSION; INCLUSIONS; VECTORS; LIVER; DNA;
Keywords:
OVINE ADENOVIRUS; SHEEP; DIAGNOSIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
26
Recensione:
Indirizzi per estratti:
Citazione:
D.B. Boyle et al., "CHARACTERIZATION OF AUSTRALIAN OVINE ADENOVIRUS ISOLATES", Veterinary microbiology, 41(3), 1994, pp. 281-291

Abstract

We have characterised two groups of adenoviruses isolated from sheep in Australia. Restriction endonuclease maps for enzymes BamHI, ClaI, SalI, SmaI and SphI have been determined for the genome of ovine adenoviruses related to bovine adenovirus serotype 7 (BAV 7) from sheep in Western Australia. Although previously serotyped as BAV 7 these isolates are different from bovine isolates of BAV 7 based on comparison withpublished restriction endonuclease profiles and maps of BAV 7 cattle isolates. Additional adenovirus isolates obtained from Victorian sheephave been serotyped as ovine adenovirus type 5 (OAV 5). On the basis of restriction endonuclease analysis these viruses are different from the sheep BAV 7 isolates. Following infection of sheep with ovine BAV 7 and OAV 5 isolates, virus was recovered from nasal and rectal swabs for several days. Antibodies detected by ELISA and serum neutralisation tests (SN) developed by 15 days after infection. Virus also spread from the infected sheep to an incontact control and one of ten sheep purchased for infection studies had SN antibodies to BAV 7 suggesting that BAV 7-like viruses naturally infect sheep in Victoria and Western Australia. With further development, these ovine adenoviruses may be suitable as vectors for the delivery of vaccine antigens to sheep and cattle.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/09/20 alle ore 10:56:20