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Titolo:
SINGLE BEAT EVALUATION OF CIRCUMFERENTIAL AORTIC ELASTIN ELASTIC-MODULUS IN CONSCIOUS DOGS - POTENTIAL APPLICATION IN NONINVASIVE MEASUREMENTS
Autore:
ARMENTANO RL; FISCHER EIC; BARRA JG; LEVENSON JA; SIMON AC; PICHEL RH;
Indirizzi:
UNIV BUENOS AIRES,FAVALORO FDN,INST BIOMED SCI,BASIC SCI RES CTR BUENOS AIRES ARGENTINA HOP BROUSSAIS,CTR MED PREVENT CARDIOVASC,INSERM,U28 F-75674 PARIS FRANCE
Titolo Testata:
Medical progress through technology
fascicolo: 1-2, volume: 20, anno: 1994,
pagine: 91 - 99
SICI:
0047-6552(1994)20:1-2<91:SBEOCA>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
ARTERIAL COMPLIANCE; HYPERTENSIVE RATS; SMOOTH-MUSCLE; PRESSURE; MECHANICS; DIAMETER; STIFFNESS; NOREPINEPHRINE; IMPEDANCE; INVITRO;
Keywords:
YOUNGS MODULUS; AORTIC WALL; STRAIN-STRESS RELATIONSHIP; ELASTIC MODULUS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
47
Recensione:
Indirizzi per estratti:
Citazione:
R.L. Armentano et al., "SINGLE BEAT EVALUATION OF CIRCUMFERENTIAL AORTIC ELASTIN ELASTIC-MODULUS IN CONSCIOUS DOGS - POTENTIAL APPLICATION IN NONINVASIVE MEASUREMENTS", Medical progress through technology, 20(1-2), 1994, pp. 91-99

Abstract

A description of the arterial wall elastic properties comprehends both collagen and elastin, clearly shown in a biphasic stress-strain relationship. From chronically instrumented conscious dogs, aortic pressure-diameter curves can be obtained in a single beat, which is impossible to perform in human beings. In control conditions, the collagen fibers are almost not distended and the resistance to stretch is mainly supported by the elastin fibers. Therefore, the mechanical properties ofthe aorta are almost purely elastic in the basal beat to beat conditions. In this study we propose and test five indexes, which include as variables: systolic, diastolic and mean arterial pressure and diameter; besides, arterial compliance and pressure-strain elastic modulus as suggested to evaluate the elastic behaviour of the elastic fibers. This data can be easily obtained by non-invasive methods, such as Doppler-ultrasound techniques and auscultative esphygmomanometrical measurements, while the indexes evaluated can be retrieved from a single beat evaluation. Of three measurements performed in chronically instrumentedconscious dogs on different days, one of these indexes, the ME(5) = P-mean x R(mean) - P-dias x R(dias)/R(mean) - R(dias) x R(dias) proved to be an accurate and reliable parameter to evaluate the mechanical behaviour of arteries. This kind of parameter may be useful for researchand evaluation of several diseases that markedly alter the arterial wall compliance.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 14/07/20 alle ore 19:05:03