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Titolo:
SCREENING-TEST FOR GROWTH-HORMONE DEFICIENCY - USEFULNESS OF L-DOPA-PROPRANOLOL PROVOCATIVE TEST
Autore:
LIM YJ; KWAN E; LOW LCK;
Indirizzi:
UNIV HONG KONG,QUEEN MARY HOSP,DEPT PAEDIAT HONG KONG HONG KONG UNIV HONG KONG,QUEEN MARY HOSP,DEPT PAEDIAT HONG KONG HONG KONG
Titolo Testata:
Journal of paediatrics and child health
fascicolo: 4, volume: 30, anno: 1994,
pagine: 328 - 330
SICI:
1034-4810(1994)30:4<328:SFGD-U>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
SHORT STATURE; CHILDREN; SECRETION; STIMULATION; ADOLESCENTS; CLONIDINE; EXCRETION; RELEASE; TERM; GH;
Keywords:
GROWTH HORMONE DEFICIENCY; L-DOPA-PROPRANOLOL PROVOCATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
32
Recensione:
Indirizzi per estratti:
Citazione:
Y.J. Lim et al., "SCREENING-TEST FOR GROWTH-HORMONE DEFICIENCY - USEFULNESS OF L-DOPA-PROPRANOLOL PROVOCATIVE TEST", Journal of paediatrics and child health, 30(4), 1994, pp. 328-330

Abstract

This is a retrospective review of 185 short children who were tested for growth hormone (GH) secretion using the L-dopa-propranolol provocative test. One hundred and thirty-three children were deemed to have passed the screening test when a GH concentration of greater than 15 miu/L was elicited after stimulation. Fifty-two failed the screening test, of which 33 were diagnosed as having growth hormone deficiency (GHD) when they had inadequate growth hormone response to insulin-induced hypoglycaemia. The other 19 were low-responders since they showed adequate GH response to insulin tolerance test (ITT). The low-responder rate to L-dopa-propranolol provocative test among short children who arenot GH deficient was 12.5%. The low cost of L-dopa and propranolol, the simplicity and safety of the test, and the acceptable rate of low-responders make the test an effective screening test for GHD.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 08/07/20 alle ore 07:59:07