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Titolo:
THE MATING-TYPE REGION OF SCHIZOSACCHAROMYCES-POMBE CONTAINS AN ESSENTIAL GENE ENCODING A PROTEIN HOMOLOGOUS TO HUMAN MODULATORS OF HIV TRANSACTIVATION
Autore:
MICHAEL H; SCHMIDT H; FLECK O; GUTZ H; LIEDTKE C; LORENTZ A; OSTERMANN K;
Indirizzi:
TECH UNIV CAROLO WILHELMINA BRAUNSCHWEIG,BIOZENTRUM,INST GENET,POSTFACH 3329 D-38023 BRAUNSCHWEIG GERMANY
Titolo Testata:
Gene
fascicolo: 2, volume: 145, anno: 1994,
pagine: 205 - 210
SICI:
0378-1119(1994)145:2<205:TMROSC>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
TAT-BINDING-PROTEIN; FISSION YEAST; FAMILY; MEMBER; CDNA; ACTIVATION; SECRETION; ELEMENT; CELLS; VCP;
Keywords:
RECOMBINANT DNA; FISSION YEAST; H(-L) DELETION; ATPASE; MULTIGENE FAMILY;
Tipo documento:
Note
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
32
Recensione:
Indirizzi per estratti:
Citazione:
H. Michael et al., "THE MATING-TYPE REGION OF SCHIZOSACCHAROMYCES-POMBE CONTAINS AN ESSENTIAL GENE ENCODING A PROTEIN HOMOLOGOUS TO HUMAN MODULATORS OF HIV TRANSACTIVATION", Gene, 145(2), 1994, pp. 205-210

Abstract

In Schizosaccharomyces pombe, an intrachromosomal crossover between the mating type (MT) expression locus and one of the silent donor cassettes is lethal due to the loss of the intervening L region. The regioncontains one essential gene, let1. This gene was cloned and sequenced. The deduced amino acid (aa) sequence of let1 shows extensive homologies with SUG1 from Saccharomyces cerevisiae. Significant homologies were also found with the human HIV transactivation modulators, MSS1 and TBP-1, as well as with subunit 4 of the mammalian 26 S protease. The data indicate that let1 is a member of a recently defined multigene family of ATPases.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/09/20 alle ore 06:42:04