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Titolo:
ARE WE REALLY ALLERGIC TO MOSQUITO BITES
Autore:
REUNALA T; BRUMMERKORVENKONTIO H; PALOSUO T;
Indirizzi:
UNIV HELSINKI,CENT HOSP,DEPT DERMATOL,MEILAHDENTIE 2 SF-00250 HELSINKI FINLAND UNIV HELSINKI,DEPT DERMATOL HELSINKI FINLAND UNIV HELSINKI,ALLERG & SKIN DIS HOSP HELSINKI FINLAND NATL PUBL HLTH INST HELSINKI FINLAND
Titolo Testata:
Annals of medicine
fascicolo: 4, volume: 26, anno: 1994,
pagine: 301 - 306
SICI:
0785-3890(1994)26:4<301:AWRATM>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
ANTIBODIES; CETIRIZINE;
Keywords:
AEDES MOSQUITOS; IGE ANTIBODIES; IMMUNOBLOTTING; TYPE I REACTION; CUTANEOUS LATE-PHASE REACTION; ANTIHISTAMINES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
28
Recensione:
Indirizzi per estratti:
Citazione:
T. Reunala et al., "ARE WE REALLY ALLERGIC TO MOSQUITO BITES", Annals of medicine, 26(4), 1994, pp. 301-306

Abstract

Most, if not all, people are sensitized to mosquito bites in childhood. Cutaneous symptoms include immediate wheal-and-flare reactions and delayed bite papules, which tend to be more severe at the onset of themosquito season. Systemic reactions to mosquito bites are, however, very rare. Recent immunoblot studies have demonstrated IgE antibodies to Aedes communis mosquito saliva 22 and 36 kD proteins. This confirms that specific sensitization occurs in man and indicates that mosquito-bite whealing is a classic type I allergic reaction. The delayed mosquito-bite papules seem to be cutaneous late-phase reactions mediated byeosinophils or they could also represent type IV lymphocyte-mediated immune reactions. People living in heavily infested areas such as Lapland frequently acquire tolerance to mosquito bites, and seem to have negligible levels of IgE but high amounts of lgG4 antisaliva antibodies. Desensitization treatment is a theoretical possibility but prophylactically given cetirizine, an H-1-blocking antihistamine, has been shown to be helpful for people suffering from mosquito bites.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 14/07/20 alle ore 11:54:32