Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
CORONARY-ARTERY STENOSIS AND OCCLUSION - VALUE OF TC-99M-MIBI SPECT
Autore:
GYONGYOSI M; MAUL FD; STANDKE R; KLEPZIG H; KALTENBACH M; HOR G;
Indirizzi:
UNIV FRANKFURT,DEPT CARDIOL W-6000 FRANKFURT GERMANY UNIV FRANKFURT,DEPT NUCL MED W-6000 FRANKFURT GERMANY
Titolo Testata:
Nuclear medicine communications
fascicolo: 8, volume: 15, anno: 1994,
pagine: 593 - 603
SICI:
0143-3636(1994)15:8<593:CSAO-V>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACUTE MYOCARDIAL-INFARCTION; METHOXY ISOBUTYL ISONITRILE; PERFUSION IMAGING AGENTS; VENTRICULAR-FUNCTION; RADIONUCLIDE VENTRICULOGRAPHY; VIABLE MYOCARDIUM; SESTAMIBI SPECT; HEART-DISEASE; TECHNETIUM I; TL-201;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
62
Recensione:
Indirizzi per estratti:
Citazione:
M. Gyongyosi et al., "CORONARY-ARTERY STENOSIS AND OCCLUSION - VALUE OF TC-99M-MIBI SPECT", Nuclear medicine communications, 15(8), 1994, pp. 593-603

Abstract

The aim of this study was to evaluate and validate a new quantification method for Tc-99m-sestamibi single photon emission computed tomographic (SPECT) myocardial imaging based on a four-slice analysis method and to check the functional results of percutaneous transluminal coronary angioplasty (PTCA). Using the calculated pathological area of the scintigram as an index for myocardial ischaemia, the overall sensitivity was 81-90% and the overall specificity was 74-98%. Analysis of variance of the repeated measurements revealed good reproducibility (coefficient of variation 8.4%). A significant correlation was found betweenthe size of the exercise-induced perfusion defects and the degree of coronary stenosis. The comparison of radionuclide ventriculography andthe perfusion image in 27 patients revealed a good correlation between the resting global ejection fraction and myocardial perfusion, but there was no correlation during exercise, indicating a dissociation between myocardial perfusion and function during exercise conditions in patients with coronary artery disease (CAD). Patients with total coronary occlusions showed more resting defects than patients with partial stenoses. Both groups benefit from PTCA or re-opening of chronic coronary occlusion, respectively. Exercise-induced myocardial ischaemia significantly decreased, and in 36% of the patients with previous myocardial infarction a significant reduction of the size of the resting perfusion defects occurred. In conclusion, our quantification method is suitable for the accurate non-invasive diagnosis of CAD, and for the follow-up of the invasive treatment of coronary artery stenoses and occlusions.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 09:56:47