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Titolo:
CARDIOVASCULAR REACTIVITY AND THE COURSE OF IMMUNE-RESPONSE TO AN ACUTE PSYCHOLOGICAL STRESSOR
Autore:
HERBERT TB; COHEN S; MARSLAND AL; BACHEN EA; RABIN BS; MULDOON MF; MANUCK SB;
Indirizzi:
CARNEGIE MELLON UNIV,DEPT PSYCHOL PITTSBURGH PA 15213 UNIV PITTSBURGH,DEPT PSYCHOL,BEHAV PHYSIOL LAB PITTSBURGH PA 15260 UNIV PITTSBURGH,SCH MED,DEPT PATHOL PITTSBURGH PA 00000 UNIV PITTSBURGH,SCH MED,DIV CLIN PHARMACOL PITTSBURGH PA 00000
Titolo Testata:
Psychosomatic medicine
fascicolo: 4, volume: 56, anno: 1994,
pagine: 337 - 344
SICI:
0033-3174(1994)56:4<337:CRATCO>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
MENSTRUAL-CYCLE; SEX-DIFFERENCES; PERIPHERAL-BLOOD; INDIVIDUAL-DIFFERENCES; BEHAVIORAL STRESS; GENDER RELEVANCE; CELLS; HUMANS; MOOD;
Keywords:
CARDIOVASCULAR REACTIVITY; GENDER; ACUTE PSYCHOLOGICAL STRESSOR; CELLULAR IMMUNE RESPONSE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social Sciences Citation Index
Social Sciences Citation Index
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
29
Recensione:
Indirizzi per estratti:
Citazione:
T.B. Herbert et al., "CARDIOVASCULAR REACTIVITY AND THE COURSE OF IMMUNE-RESPONSE TO AN ACUTE PSYCHOLOGICAL STRESSOR", Psychosomatic medicine, 56(4), 1994, pp. 337-344

Abstract

This study evaluated the temporal nature of cellular immune responses, as well as the effects of cardiovascular reactivity on immune responses after exposure to an acute psychological stressor. Lymphocyte subsets and lymphocyte proliferative response to phytohemagglutinin were assessed at baseline and at 5 and 21 minutes after stressor onset in the experimental group and at the same time points in a nonstressor control group. By 5 minutes after stressor onset, the number of CD8 suppressor/cytotoxic T and CD16/56 natural killer cells increased and proliferative response to phytohemagglutinin decreased. These changes were maintained at 21 minutes. Those subjects showing the greatest cardiovascular reactivity had the largest immune alterations. These data did not indicate that gender significantly moderated immune responses. Results are consistent with the hypothesis that sympathetic activation mediates stressor-induced quantitative alterations of peripheral blood lymphocyte subpopulations and nonspecific mitogen stimulated proliferation.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 10:54:43