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Titolo:
ANTIRETROVIRAL THERAPY FOR INFECTION DUE TO HUMAN-IMMUNODEFICIENCY-VIRUS IN CHILDREN
Autore:
PIZZO PA; WILFERT C;
Indirizzi:
NCI,PEDIAT BRANCH,BLDG 10,ROOM 13N240 BETHESDA MD 20892 DUKE UNIV,MED CTR,DEPT PEDIAT DURHAM NC 27710
Titolo Testata:
Clinical infectious diseases
fascicolo: 1, volume: 19, anno: 1994,
pagine: 177 - 196
SICI:
1058-4838(1994)19:1<177:ATFIDT>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
PNEUMOCYSTIS-CARINII PNEUMONIA; HIV-1 REVERSE-TRANSCRIPTASE; AIDS-RELATED COMPLEX; POLYMERASE CHAIN-REACTION; RECOMBINANT SOLUBLE CD4; PLACEBO-CONTROLLED TRIAL; INFUSION ZIDOVUDINE THERAPY; HIGH-LEVEL RESISTANCE; P24 ANTIGEN LEVELS; PHASE-I TRIAL;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
179
Recensione:
Indirizzi per estratti:
Citazione:
P.A. Pizzo e C. Wilfert, "ANTIRETROVIRAL THERAPY FOR INFECTION DUE TO HUMAN-IMMUNODEFICIENCY-VIRUS IN CHILDREN", Clinical infectious diseases, 19(1), 1994, pp. 177-196

Abstract

Infection with human immunodeficiency virus type 1 (HIV-1) in children presents problems that greatly differ from those seen in adults. Thegreat majority of children are infected either during gestation or atthe time of birth. As Drs. Pizzo and Wilfert note in their AIDS Commentary, this results in rapid development of immunosuppression and clinical manifestations in patients whose immune systems are in the process of maturing. Thus, a thorough understanding of the pharmacokinetics of antiretroviral agents in infants and small children is required. This AIDS Commentary provides a comprehensive review of the current state of our knowledge and possible future directions for the management of HIV-1 infection in this young population.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 00:36:05