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Titolo:
QUALITATIVE MAPPING OF CEREBRAL BLOOD-FLOW AND FUNCTIONAL LOCALIZATION WITH ECHO-PLANAR MR-IMAGING AND SIGNAL TARGETING WITH ALTERNATING RADIO-FREQUENCY
Autore:
EDELMAN RR; SIEWERT B; DARBY DG; THANGARAJ V; NOBRE AC; MESULAM MM; WARACH S;
Indirizzi:
BETH ISRAEL HOSP,DEPT RADIOL,330 BROOKLINE AVE BOSTON MA 02215 BETH ISRAEL HOSP,DEPT NEUROL BOSTON MA 02215 HARVARD UNIV,SCH MED BOSTON MA 02215 UNIV BONN,DEPT RADIOL BONN GERMANY
Titolo Testata:
Radiology
fascicolo: 2, volume: 192, anno: 1994,
pagine: 513 - 520
SICI:
0033-8419(1994)192:2<513:QMOCBA>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
FREELY DIFFUSIBLE TRACER; HUMAN-BRAIN-FUNCTION; SENSORY STIMULATION; COGNITIVE ACTIVITY; ANGIOGRAPHY; INVERSION; CORTEX; REST; NMR;
Keywords:
CEREBRAL BLOOD VESSELS, FLOW DYNAMICS; MAGNETIC RESONANCE (MR), ECHO PLANAR; MAGNETIC RESONANCE (MR), VASCULAR STUDIES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
25
Recensione:
Indirizzi per estratti:
Citazione:
R.R. Edelman et al., "QUALITATIVE MAPPING OF CEREBRAL BLOOD-FLOW AND FUNCTIONAL LOCALIZATION WITH ECHO-PLANAR MR-IMAGING AND SIGNAL TARGETING WITH ALTERNATING RADIO-FREQUENCY", Radiology, 192(2), 1994, pp. 513-520

Abstract

PURPOSE: To create qualitative maps of cerebral blood flow (CBF) withthe EPISTAR (echo-planar imaging and signal targeting with alternating radio frequency) technique. MATERIALS AND METHODS: The EPISTAR technique was performed in a pig model of hypercapnia and then tested in 26volunteers by using various paradigms for cortical activation. Echo-planar images were acquired with and without use of a radio-frequency inversion pulse applied to inflowing arterial spins. A qualitative map of CBF was then created by subtracting the image obtained without the radio-frequency pulse from that obtained with the radio-frequency pulse. RESULTS: Progressively more distal portions of the tagged vessels were seen as the inflow time was lengthened until cortical enhancement was seen for inflow times of approximately 1 second or longer. Signal intensity increases from rest to sensorimotor activation ranged from 13% to 193%. CBF changes in the motor strip, primary visual cortex, andthe motor area for eye movements were well localized to the cortical gray matter ribbon. CONCLUSION: The EPISTAR technique is a rapid, noninvasive means for creating qualitative maps of CBF.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/07/20 alle ore 14:11:58