Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
APOPTOSIS - PROGRAMMED CELL-DEATH IN HEALTH AND DISEASE
Autore:
BRIGHT J; KHAR A;
Indirizzi:
CTR CELLULAR & MOLEC BIOL,UPPAL RD HYDERABAD 500007 INDIA CTR CELLULAR & MOLEC BIOL HYDERABAD 500007 INDIA
Titolo Testata:
Bioscience reports
fascicolo: 2, volume: 14, anno: 1994,
pagine: 67 - 81
SICI:
0144-8463(1994)14:2<67:A-PCIH>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
ADENOVIRUS E1A PROTEINS; NATURAL-KILLER CELLS; C-MYC; DNA FRAGMENTATION; CAENORHABDITIS-ELEGANS; T-CELLS; THYMOCYTE APOPTOSIS; MURINE THYMOCYTES; SIGNAL DELIVERY; IMMUNE-SYSTEM;
Keywords:
APOPTOSIS; PROGRAMMED CELL DEATH;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
104
Recensione:
Indirizzi per estratti:
Citazione:
J. Bright e A. Khar, "APOPTOSIS - PROGRAMMED CELL-DEATH IN HEALTH AND DISEASE", Bioscience reports, 14(2), 1994, pp. 67-81

Abstract

Apoptosis is a normal physiological cell death process of eliminatingunwanted cells from living organisms during embryonic and adult development. Apoptotic cells are characterised by fragmentation of nuclear DNA and formation of apoptotic bodies. Genetic analysis revealed the involvement of many death and survival genes in apoptosis which are regulated by extracellular factors. There are multiple inducers and inhibitors of apoptosis which interact with target cell specific surface receptors and transduce the signal by second messengers to programme cell death. The regulation of apoptosis is elusive, but defective regulation leads to aetiology of various ailments. Understanding the molecular mechanism of apoptosis including death genes. death signals. surfacereceptors and signal pathways will provide new insights in developingstrategies to regulate the cell survival/death. The current knowledgeon the molecular events of apoptotic cell death and their significance in health and disease is reviewed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 15/07/20 alle ore 14:01:43