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Titolo:
CELL REPRODUCTION - INDUCTION OF M-PHASE EVENTS BY CYCLIN-DEPENDENT CDC2 KINASE
Autore:
KISHIMOTO T;
Indirizzi:
TOKYO INST TECHNOL,FAC BIOSCI,CELL & DEV BIOL LAB,NAGATSUTA,MIDORI KUYOKOHAMA KANAGAWA 227 JAPAN
Titolo Testata:
The International journal of developmental biology
fascicolo: 2, volume: 38, anno: 1994,
pagine: 185 - 191
SICI:
0214-6282(1994)38:2<185:CR-IOM>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
MATURATION-PROMOTING FACTOR; MICROTUBULE NUCLEATING ACTIVITY; PROTEIN-KINASE; STARFISH OOCYTES; PHOSPHORYLATION SITES; MEIOSIS REINITIATION; MEIOTIC MATURATION; CATALYTIC SUBUNIT; P34CDC2 KINASE; HISTONE H1;
Keywords:
CDC2 KINASE; CYCLIN-B; M-PHASE EVENTS; CHROMOSOME CONDENSATION; SPINDLE FORMATION;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
65
Recensione:
Indirizzi per estratti:
Citazione:
T. Kishimoto, "CELL REPRODUCTION - INDUCTION OF M-PHASE EVENTS BY CYCLIN-DEPENDENT CDC2 KINASE", The International journal of developmental biology, 38(2), 1994, pp. 185-191

Abstract

Although a major concern in the development of multicellular organisms is cell differentiation, the construction of a multicellular system essentially depends on cell multiplication, which consists of genomic duplication and segregation. Recent progress has revealed that cyclin-dependent kinases (CDKs) are key components of a cell cycle engine that governs cell proliferation. This article focuses on how CDKs induce M-phase events characterized by nuclear membrane breakdown, chromosomecondensation and mitotic spindle formation to assure genomic segregation.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 01:16:12