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Titolo:
A RETROSPECTIVE ANALYSIS OF THE COST-EFFECTIVENESS OF TREATMENT WITH METASTRON(R) (SR-89-CHLORIDE) IN PATIENTS WITH PROSTATE-CANCER METASTATIC TO BONE
Autore:
MCEWAN AJB; AMYOTTE GA; MCGOWAN DG; MACGILLIVRAY JA; PORTER AT;
Indirizzi:
CROSS CANC INST,11560 UNIV AVE EDMONTON T6G 1Z2 ALBERTA CANADA GERSHENSON RADIAT ONCOL CTR DETROIT MI 00000
Titolo Testata:
Nuclear medicine communications
fascicolo: 7, volume: 15, anno: 1994,
pagine: 499 - 504
SICI:
0143-3636(1994)15:7<499:ARAOTC>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
PAIN PALLIATION; SR-89; TRIAL; MANAGEMENT; CARCINOMA; EFFICACY; ADJUVANT; THERAPY; HEALTH;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
21
Recensione:
Indirizzi per estratti:
Citazione:
A.J.B. Mcewan et al., "A RETROSPECTIVE ANALYSIS OF THE COST-EFFECTIVENESS OF TREATMENT WITH METASTRON(R) (SR-89-CHLORIDE) IN PATIENTS WITH PROSTATE-CANCER METASTATIC TO BONE", Nuclear medicine communications, 15(7), 1994, pp. 499-504

Abstract

The objectives of the study were to estimate the cost of medical carefor patients recruited into the Trans Canada trial of Metastron(R) (Sr-89-chloride) as adjunct therapy in patients with prostate cancer metastatic to bone and to compare the costs of those receiving Metastron with those receiving placebo. Data from case report forms, hospital records and, where necessary, telephone follow-up were used. Twenty-ninepatients, recruited into the trial at the Cross Cancer Institute, were followed from time of entry into the trial over the balance of theirlifetime. Data were costed by reference to fee schedule, pharmacy andgovernment and hospital defined costs as indirect (investigations, outpatient visits and total and tertiary hospital inpatient days) and direct (analgesics, hormones, radiotherapy and transfusions). Meaningfuldifferences in analgesic, hormone and radiotherapy costs were seen between the two groups, with the group receiving Metastron showing a lifetime reduction of Can $1720 per person when compared with placebo. A reduction of Can $5696 per patient in the Metastron group was shown based upon requirements for admission for tertiary care; however, if total hospital stay costs are calculated there is no difference between the two groups. This retrospective study suggests that treatment with Metastron can bring about meaningful reductions in lifetime management costs in patients with advanced prostate cancer. These findings shouldbe correlated with the significant improvement in quality of life reported in the Trans Canada study and appear to offer financial support to the clinical rationale for the use of Metastron in the palliative treatment of these patients.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 18:32:07